Research Topic: kidney disease

Increased Rates of Supplement-Associated Oxalate Nephropathy During COVID-19 Pandemic

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During the COVID-19 pandemic, more people took dietary supplements and high-dose vitamin C for health reasons. However, this study found that excessive supplement intake led to a significant increase in a kidney disease called oxalate nephropathy, where calcium oxalate crystals damage the kidneys. The good news is that when patients stopped taking these harmful supplements, their kidney function often improved, emphasizing the importance of careful supplement use.

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Ganoderma lucidum and Robinia pseudoacacia Flower Extract Complex Alleviates Kidney Inflammation and Fibrosis by Modulating Oxidative Stress

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Researchers studied a natural supplement made from reishi mushroom and black locust flower to treat kidney disease. In laboratory and animal tests, this supplement reduced kidney damage by lowering harmful molecules called free radicals and controlling inflammation. The supplement worked by blocking specific pathways that cause kidney inflammation and scarring, suggesting it could be a helpful natural treatment for people with chronic kidney disease.

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Global research hotspots and trends in oxidative stress-related diabetic nephropathy: a bibliometric study

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This study analyzed over 4,000 research papers published between 2014 and 2024 about how oxidative stress damages kidneys in diabetic patients. Researchers found that China and the United States lead this research field, with increasing focus on natural compounds and traditional medicines that can reduce harmful reactive oxygen species. The findings suggest future treatments for diabetic kidney disease should target oxidative stress through both conventional drugs and natural antioxidant compounds derived from plants and fungi.

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A cross-sectional study of the association between plant-based diet indices and kidney stones among Iranian adults

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A study of nearly 10,000 Iranian adults found that people who followed a plant-based diet had a higher risk of developing kidney stones. However, the quality of plant-based eating did not matter—neither healthful nor unhealthful plant-based diets changed the risk significantly. This suggests that while plant-based diets are generally healthy, people at risk for kidney stones should ensure adequate calcium intake and proper hydration.

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Natural Products in Renal-Associated Drug Discovery

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This research examines how natural products like green tea and medicinal mushrooms can help treat kidney diseases. Scientists reviewed various plants used in traditional medicine and analyzed how compounds from these plants affect gene expression in kidney cells. The study identified specific genes and biological pathways that explain how these natural antioxidants and anti-inflammatory agents protect kidneys from injury and disease.

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