Hematology – mycolab.ai

Invasive Trichoderma longibrachiatum breakthrough infection in a hematology patient

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A 61-year-old woman with blood cancer developed a severe and unusual double fungal infection caused by two mold species while being treated for a known fungal infection. Despite receiving multiple antifungal medications, her condition worsened and she ultimately died from multiple organ failure. The case is important because it demonstrates how Trichoderma fungi are becoming dangerous pathogens in very sick, immunocompromised patients, and a new drug called olorofim showed promising activity against this infection in laboratory tests.

Splenic Infarct: A Rare Complication of Infectious Mononucleosis in a Monospot-Negative Patient

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A 21-year-old woman came to the hospital with fever, jaundice, and abdominal pain that persisted despite antibiotics. Although her monospot test for mononucleosis came back negative, blood tests for a virus called Epstein-Barr Virus (EBV) confirmed she had infectious mononucleosis. Imaging scans revealed multiple areas of dead tissue (infarcts) in her spleen caused by blocked blood vessels. She recovered well with rest and supportive care, highlighting how mononucleosis can sometimes cause serious complications even when the initial screening test is negative.

Research Topic: Hematology

Invasive Trichoderma longibrachiatum breakthrough infection in a hematology patient

Splenic Infarct: A Rare Complication of Infectious Mononucleosis in a Monospot-Negative Patient