Research Topic: fungal infection

Severe tinea faciei mimicking favus-like lesions linked to rabbit exposure: A case report

A young girl developed facial rashes after getting a pet rabbit and was initially treated for eczema, but her condition worsened. Tests revealed she and her rabbit both had a fungal infection caused by Trichophyton mentagrophytes. The infection was successfully treated with oral antifungal medication. This case highlights how pet contact can transmit fungal infections to children and the importance of proper diagnosis before starting treatment.

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Early changes in microRNA expression in Arabidopsis plants infected with the fungal pathogen Fusarium graminearum

Researchers studied how Arabidopsis plants respond to infection by the fungus Fusarium graminearum by examining changes in small RNA molecules called microRNAs. They found that the plant activates specific microRNAs early in infection, even before visible disease symptoms appear. Two particularly important microRNAs, miR855 and miR826a, were identified as potential key regulators of the plant’s defense response. These findings could help scientists develop crop varieties with improved resistance to fungal diseases that cause significant agricultural losses worldwide.

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Infection of Norway spruce by Chrysomyxa rhododendri: ultrastructural insights into plant–pathogen interactions reveal differences between resistant and susceptible trees

Researchers studied how a rust fungus infects Norway spruce trees at the microscopic level, comparing healthy, resistant trees with ones that get severely infected. In resistant trees, the plant quickly builds protective barriers and accumulates compounds called tannins that slow down the fungus. Understanding these natural defenses could help foresters choose and grow spruce trees that better resist this devastating disease in high-altitude forests.

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Frequency and Distribution of Broncho-Alveolar Fungi in Lung Diseases in Martinique

This study examined fungal samples from the lungs of over 1500 patients in Martinique using a special procedure called broncho-alveolar lavage. Researchers found that fungi were very common in respiratory samples, with specific types of fungi appearing more frequently in different lung diseases. For example, certain mold-like fungi were more common in patients with bronchiectasis (damaged airways), while yeast-like fungi were more common in patients with pneumonia. The findings suggest that tropical climate and environmental conditions significantly influence which fungi colonize the lungs.

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The Involvement of Glycerophospholipids in Susceptibility of Maize to Gibberella Root Rot Revealed by Comparative Metabolomics and Mass Spectrometry Imaging Joint Analysis

Maize plants can suffer from a serious root disease called Gibberella root rot caused by a fungus. Researchers studied two types of maize—one resistant and one susceptible to this disease—and found that certain fatty compounds called lysophospholipids are more abundant in the susceptible plants. When these compounds build up, they damage plant cells and help the fungus spread. The resistant plants can break down these harmful compounds more effectively. This discovery could help plant breeders create maize varieties that resist this damaging disease.

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Surgical management of deep dermatophytosis in a patient with CARD9 deficiency

A 23-year-old man from North Africa with a genetic immune disorder (CARD9 deficiency) developed a serious fungal skin infection with deep tissue involvement. The infection caused multiple pus-filled pockets and hair loss on his scalp. Doctors treated him with both antifungal medications and surgery to drain the infected areas, resulting in complete healing after two weeks.

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A case of rare fungal keratitis caused by Pseudoshiraia conidialis

A 61-year-old woman scratched her eye with a bamboo branch and developed a serious fungal eye infection caused by a rare fungus called Pseudoshiraia conidialis. This is the first reported case of this particular fungus infecting human eyes. Although initial treatment with antifungal medications showed promise, the infection proved difficult to cure due to the fungus being resistant to multiple antifungal drugs. The case highlights the importance of early diagnosis and treatment of fungal eye infections.

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Deep cutaneous fungal infection in an immunocompetent individual caused by a biological pesticide: a rare case report

A 66-year-old farmer developed a deep skin fungal infection from a biological pesticide she used for over 10 years. The pesticide contained a fungus called Purpureocillium lilacinum, which is normally harmless to healthy people but caused repeated skin lesions on her face and arms. She was successfully treated with antifungal medication (itraconazole) for three months, and her skin fully healed without returning. This is the first reported case showing that biological pesticides can pose health risks to workers who handle them regularly.

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Disseminated Scytalidium philadelphianum infection in a Belgian Malinois

A Belgian Malinois dog developed a serious fungal infection caused by Scytalidium philadelphianum, a rare mold, that affected the spine and eventually the brain. The infection was diagnosed through imaging, fluid samples, and fungal culture from the dog’s urine and spine tissue. Despite treatment with multiple antifungal medications over seven months, the dog’s condition worsened with seizures and nerve damage, leading to euthanasia. This case marks the first documented instance of this particular fungal species causing widespread disease in animals.

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Changes in the microflora on the seed surface and seed vigor of maize (Zea mays) under different conditions

This study examined how different humidity levels during seed storage affect the types of fungi that grow on maize seeds and how this impacts seed quality. Researchers found that high humidity causes different fungi to colonize seeds and dramatically reduces the seeds’ ability to germinate and grow. The fungi harm seeds by producing toxins and reducing their energy production, making stored seeds much less viable for farming.

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