Research Topic: fungal cell wall

Phospholipase PlcH is involved in the secretion of cell wall glycoproteins and contributes to the host immune response of Aspergillus fumigatus

Researchers discovered that an enzyme called PlcH helps a dangerous mold called Aspergillus fumigatus release protective proteins into its cell wall. These proteins help the fungus survive and evade the immune system. When scientists removed the gene for PlcH, the fungus became weaker and more vulnerable to both antifungal drugs and immune cells, suggesting PlcH could be a target for new antifungal treatments.

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Nitric Oxide-Mediated Regulation of Chitinase Activity and Cadmium Sequestration in the Response of Schizophyllum commune to Cadmium Stress

A culinary mushroom called Schizophyllum commune can be harmed by cadmium pollution. When exposed to cadmium, the fungus produces nitric oxide, which causes enzymes called chitinases to become more active. These active enzymes break down the mushroom’s cell wall, allowing more cadmium to accumulate and ultimately damage the fungus’s growth. By reducing nitric oxide levels, scientists may be able to protect this mushroom from cadmium poisoning.

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