drug delivery systems

Synthesis of fungal polysaccharide-based nanoemulsions for cancer treatment

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Researchers developed tiny capsules (nanoemulsions) made from corn protein and chitosan to better deliver shiitake mushroom compounds to treat cancer and reduce inflammation. When shiitake extract was enclosed in these nano-sized carriers, it became much more effective at killing breast cancer cells, fighting bacteria, and reducing inflammation compared to using the mushroom extract alone. This technology could lead to new natural medicines and health supplements that are more effective at lower doses.

Leveraging polysaccharide-derived nanocarriers to open new horizons in oral vaccine activation

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Oral vaccines are easier to administer than injections, but the stomach’s harsh environment destroys them before they work. Scientists are developing special nanocarrier particles made from natural plant materials, especially those used in traditional Chinese medicine, that protect vaccine ingredients and trigger stronger immune responses in the gut. These carriers work like protective vehicles that deliver vaccines safely to immune cells in the intestines, potentially revolutionizing how we vaccinate people worldwide.

Processes of Obtaining Nanostructured Materials with a Hierarchical Porous Structure on the Example of Alginate Aerogels

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Scientists created lightweight, sponge-like materials called aerogels made from alginate (a substance derived from seaweed) with special internal structures. They tested three different techniques to create these structures: using soap-like surfactants, using a plant protein called zein, and using pressurized carbon dioxide. Each method produced materials with different pore sizes and characteristics, making them suitable for different medical applications like delivering medications slowly or growing cells for tissue repair.

Latest advance anti-inflammatory hydrogel wound dressings and traditional Lignosus rhinoceros used for wound healing agents

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This review examines modern hydrogel wound dressings and traditional medicinal mushrooms like Lignosus rhinoceros for treating wounds. Hydrogels are water-absorbing materials that mimic natural tissue and help wounds heal by maintaining moisture, preventing infection, and promoting cell growth. Traditional mushrooms offer anti-microbial and anti-inflammatory properties that could complement modern dressing technologies for better wound healing outcomes.

Fungus-targeted nanomicelles enable microRNA delivery for suppression of virulence in Aspergillus fumigatus as a novel antifungal approach

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Researchers developed a new way to fight dangerous fungal infections caused by Aspergillus fumigatus by using tiny particles called nanomicelles to deliver genetic material (microRNAs) directly into fungal cells. These microRNAs target and reduce the production of melanin, a protective pigment that helps the fungus resist immune attacks. By weakening this defense, the fungal cells become more vulnerable to the body’s immune system and to stress, offering a novel approach to treat serious fungal infections that have become resistant to standard antifungal drugs.

Research Progress of Polysaccharide-Gold Nanocomplexes in Drug Delivery

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Scientists are combining polysaccharides (natural compounds found in plants and organisms) with tiny gold particles to create better drug delivery systems. These hybrid nanoparticles can transport medicines directly to cancer cells while reducing side effects and improving treatment effectiveness. The review discusses how these gold-polysaccharide combinations can also fight bacteria and viruses, making them useful for various medical applications beyond cancer therapy.

Graphene nanomaterials: A new frontier in preventing respiratory fungal infections

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Fungal lung infections are a serious problem, especially for people with weak immune systems. Researchers are exploring graphene nanomaterials as a new treatment approach that can deliver antifungal drugs directly to infected areas in the lungs. These tiny particles work by creating toxic stress inside fungal cells and breaking down their protective biofilms, while using smaller drug doses and causing fewer side effects than traditional treatments.

Fungus-targeted nanomicelles enable microRNA delivery for suppression of virulence in Aspergillus fumigatus as a novel antifungal approach

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Researchers developed a new way to fight dangerous fungal infections caused by Aspergillus fumigatus, which increasingly resists standard antifungal drugs. They used tiny molecules called microRNAs packaged in even tinier delivery vehicles to turn off genes that help the fungus survive. When these microRNAs were introduced, the fungus became much more vulnerable to the body’s immune system and to stress. This novel approach could eventually help treat infections that are otherwise difficult to cure.

Graphene nanomaterials: A new frontier in preventing respiratory fungal infections

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Graphene nanomaterials, especially nano-graphene oxide, show promise as new treatments for serious lung fungal infections that particularly threaten people with weakened immune systems. These tiny materials work by generating damaging reactive oxygen species that kill fungal cells and prevent biofilm formation. Unlike traditional antifungal drugs, nano-graphene oxide can be delivered directly to infected lung tissue via inhalation, delivering medicine exactly where needed while reducing harmful side effects throughout the body.

Agar–Agar Gels Carrying Curative and Preventive Agents Against Helminths: An In Vitro Compatibility Evaluation

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This research demonstrates that a new gel made from edible seaweed (agar-agar) can safely deliver deworming medications to animals while also containing a beneficial fungus that destroys parasite eggs in soil. Tests showed that the deworming drugs piperazine and levamisole did not interfere with the fungus’s ability to grow and reproduce. This combined approach could provide both immediate treatment and long-term prevention of parasitic infections in pets and farm animals.

Research Topic: drug delivery systems