Research Topic: diagnostics

Global status and trends of invasive pulmonary aspergillosis: A bibliometric study

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This study analyzes 24 years of research on invasive pulmonary aspergillosis, a serious fungal infection in immunocompromised patients. Using bibliometric tools, researchers mapped out how the field has evolved, identifying leading countries (USA, Germany, China), key experts like David Denning and Thomas Walsh, and shifting research focus from transplant-related infections to COVID-19-associated cases. The analysis shows the field is rapidly growing with increasing emphasis on rapid diagnostic methods and antifungal therapies.

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Complete mitochondrial genome of the fungal pathogen Fusarium oxysporum f. sp. palmarum responsible for fusarium wilt of palms

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Scientists have decoded the complete genetic instruction manual for a fungus that causes a deadly disease in palm trees. The fungus, Fusarium oxysporum f. sp. palmarum, kills palm trees by causing one-sided leaf death that spreads upward through the canopy. By sequencing the fungus’s mitochondrial genome—the energy-producing part of its cells—researchers have created a tool that can help quickly and accurately identify this pathogen in infected plants. This discovery will help nurseries and gardeners detect and prevent the spread of this destructive disease.

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Detection of Mucorales antigen in bronchoalveolar lavage samples using a newly developed lateral-flow device

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Researchers tested a new rapid test device that detects a specific protein released by dangerous mold infections (mucormycosis) in patient respiratory samples. The test uses a special antibody to identify these molds quickly, which is important because mucormycosis can be life-threatening and requires fast treatment. The device showed promise with about 77% accuracy in identifying infections, though larger studies are needed to confirm these findings.

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Glycan microarray analysis of Candida-related antibodies in human and mice sera guides biomarker discovery and vaccine development

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Researchers used a special microarray technology to identify immune responses in blood samples from people infected with Candida yeast. They found that early infections trigger antibodies against certain sugar structures, while later infections produce different antibodies. Three specific sugar molecules showed promise as markers for diagnostic tests and vaccine development against dangerous yeast infections.

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Professor Emel Tümbay (1941–2025): A Pioneer of Medical Mycology in Türkiye

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Professor Emel Tümbay was a pioneering scientist who transformed medical mycology in Türkiye from 1941 to 2025. She established the country’s first diagnostic mycology laboratory, wrote important reference books, and trained many specialists who spread her knowledge throughout the nation. Her work helped doctors better understand and treat fungal diseases, and she is remembered as a dedicated educator and passionate scientist.

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Editorial: Innovation in tackling the global challenge of eradicating antibiotic-resistant microorganisms

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Antibiotic resistance is a serious global health problem causing millions of deaths annually. Scientists are developing new approaches to fight resistant bacteria, including using bacteriophages (viruses that attack bacteria), improving detection methods, and testing plant-based compounds. This editorial discusses 15 research papers showing various innovative strategies, emphasizing that we need multiple tools working together rather than relying on any single solution to solve this complex problem.

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Keep the Hospital Clean: Diagnostic Performance of Ten Different Molecular and Culture-Based Methods to Detect Candidozyma (Candida) auris

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This study tested different methods to detect a dangerous hospital fungus called Candida auris. Researchers compared growing the fungus on special plates and using molecular tests on patient samples. They found that molecular tests (qPCR) were most sensitive for detecting low levels of the fungus, while growing it on special plates worked well for higher levels. The best approach depends on whether a hospital is dealing with an outbreak or routine screening.

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