Research Topic: dermatophytosis

Dermatophytosis in a Chilean fox: first case of Nannizzia gypsea in Lycalopex griseus and the need for a one health approach

A young wild Chilean fox was found with a skin infection caused by a fungus called Nannizzia gypsea, which lives in soil and can infect animals and humans. This is the first time this fungus has been documented in foxes anywhere. Doctors treated the fox with an antifungal cream and it recovered completely. The case highlights how increasing urbanization and contact between domestic pets, wild animals, and humans can spread fungal diseases, emphasizing the need for a coordinated public health approach.

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Wildlife Dermatophytoses in Central Italy (Umbria and Marche Regions): A Fifteen-Year Investigation (2010–2024)

Researchers studied fungal skin infections in wild animals across two Italian regions over 15 years, finding that about 11% carried dermatophyte fungi. Grey squirrels were most commonly infected, and some of these fungi can spread to humans through contact. The study highlights how wild animals act as sentinels for emerging diseases and emphasizes the importance of protective equipment when handling wildlife.

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Antifungal susceptibility testing of Microsporum canis isolated from the skin of dermatologically healthy cats

Researchers found that about 5% of healthy cats in Chile carry a fungal infection called Microsporum canis that can spread to humans. The concerning discovery is that all strains tested were resistant to fluconazole, a commonly used antifungal medication. The study shows that indoor cats are at higher risk of carrying this fungus and suggests that screening healthy cats could help prevent transmission to people who have close contact with them.

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Emergence of resistant dermatophytosis caused by Trichophyton indotineae: First case series in Thailand

Researchers in Thailand have identified five patients with a difficult-to-treat fungal skin infection caused by Trichophyton indotineae, a type of dermatophyte that resists the commonly used antifungal drug terbinafine. This is the first time this resistant fungus has been detected in Thailand. The team developed a simple, inexpensive test using urease to help identify these resistant infections more easily. Patients responded well to the antifungal drug itraconazole after other treatments failed.

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Dermatophytosis in a Chilean fox: first case of Nannizzia gypsea in Lycalopex griseus and the need for a one health approach

A wild South American grey fox found near Santiago, Chile was treated for a skin infection caused by a fungus called Nannizzia gypsea. This is the first time this particular fungus has been documented in foxes, raising concerns about how increasing contact between domestic animals, wildlife, and humans due to urbanization may spread fungal diseases. The fox was successfully treated with topical antifungal cream, and the fungus was found to be susceptible to all tested antifungal medications.

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Spread of Antifungal-Resistant Trichophyton indotineae, United Kingdom, 2017–2024

A fungal infection called Trichophyton indotineae, which originated in Asia, is rapidly spreading throughout the United Kingdom and becoming resistant to common antifungal treatments. The infection typically starts in the groin area and can spread to other parts of the body, and many cases fail to respond to standard antifungal drugs like terbinafine. Researchers tracked 157 cases over seven years and found the fungus now accounts for over a third of all dermatophyte infections sent to the UK reference laboratory. Doctors and laboratory professionals are being urged to recognize this emerging threat and consider better diagnostic and treatment strategies.

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Epidemiology of Onychomycosis in the United States Characterized Using Molecular Methods, 2015–2024

This large study examined over 710,000 nail samples to identify which fungi cause nail infections in the United States. Using modern molecular testing combined with microscopic analysis, researchers found that while the fungus T. rubrum is most common, other molds and yeasts cause many infections too. Importantly, women and older adults are more likely to have infections from these other organisms, which are often harder to treat with standard antifungal medications.

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Wildlife Dermatophytoses in Central Italy (Umbria and Marche Regions): A Fifteen-Year Investigation (2010–2024)

Researchers in central Italy studied fungal skin infections in wild animals over 15 years to understand disease patterns and public health risks. They found that about 11% of wild animals tested positive for dermatophytes (skin fungi), with some species dangerous to humans. The most common fungi found were Paraphyton mirabile and Trichophyton mentagrophytes, which can spread to people through contact with infected animals. The study highlights the importance of monitoring wildlife health and using protective equipment when handling wild animals.

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First reported Canadian case of Trichophyton mentagrophytes genotype VII infection among men who have sex with men (MSM)

A Canadian man contracted a rare fungal skin infection caused by Trichophyton mentagrophytes genotype VII during a trip to Mexico, likely through sexual contact. The infection presented as deep, painful lesions in the genital area that didn’t respond to typical treatments and required 10 weeks of oral and topical antifungal medication to cure. This is the first confirmed case in Canada and highlights the importance of doctors being aware of sexually transmitted fungal infections, especially in patients with unusual rashes that don’t improve with standard treatments.

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Emergence of resistant dermatophytosis caused by Trichophyton indotineae: First case series in Thailand

Researchers in Thailand identified five patients with a new type of fungal skin infection caused by Trichophyton indotineae, a species that resists the common antifungal drug terbinafine. These infections appeared as rashes on various parts of the body and required treatment with alternative medications like itraconazole. The findings represent the first confirmed cases in Thailand and suggest this resistant fungus may be spreading globally. The study also showed that a simple urease test could help doctors identify this resistant strain quickly without waiting for complex genetic testing.

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