Research Topic: chemotherapy side effects

Polysaccharides from Spores of Cordyceps cicadae Protect against Cyclophosphamide-Induced Immunosuppression and Oxidative Stress in Mice

Researchers extracted and studied special compounds called polysaccharides from the spores of Cordyceps cicadae, a medicinal fungus used in traditional Chinese medicine. When tested in mice treated with a cancer drug that suppresses immunity, one of these purified compounds (CCSP-2) successfully restored immune function and reduced harmful oxidative stress. The compound works by boosting the activity of immune cells and protecting the body’s natural antioxidant defense systems, suggesting it could potentially help cancer patients manage chemotherapy side effects.

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Medicinal Plants for Chemotherapy-Induced Nausea and Vomiting: A Systematic Review of Antiemetic, Chemosensitizing, and Immunomodulatory Mechanisms

This review examines how medicinal plants can help manage nausea and vomiting caused by cancer chemotherapy. Over 22 plants including ginger, cannabis, mint, and turmeric work through multiple mechanisms like blocking serotonin pathways and reducing inflammation. Beyond reducing symptoms, these plants may also enhance chemotherapy effectiveness and boost immune function. The research suggests combining medicinal plants with standard cancer treatments could improve patient outcomes and quality of life.

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