bioprocess engineering

A Model-Driven Approach to Assessing the Fouling Mechanism in the Crossflow Filtration of Laccase Extract from Pleurotus ostreatus 202

mycolabadmin

Scientists developed a method to purify laccase enzymes from oyster mushrooms using membrane filtration technology. They compared mathematical models to predict how membranes get clogged during filtration and found that using crossflow (tangential) filtration significantly reduces harmful clogging. Understanding these clogging patterns helps improve enzyme purification for use in industrial applications like textile processing and bioremediation.

Advances in Bioprocess Engineering for Optimising Chlorella vulgaris Fermentation: Biotechnological Innovations and Applications

mycolabadmin

Chlorella vulgaris is a nutrient-rich microalga gaining popularity in health supplements, functional foods, and sustainable energy production. Scientists are using advanced genetic engineering techniques, special fermentation methods, and innovative bioreactor designs to increase the production of beneficial compounds like proteins and antioxidants. These improvements make Chlorella more valuable for creating health-promoting foods, medicines, and biofuels while keeping production costs low and environmentally sustainable.

Airlift bioreactor–based strategies for prolonged semi-continuous cultivation of edible Agaricomycetes

mycolabadmin

Scientists studied how to grow medicinal mushrooms in liquid bioreactors to produce health-beneficial compounds called glucans more efficiently. By testing different feeding rates in specially designed fermentation systems, they found that Trametes versicolor (turkey tail mushroom) grows best at a moderate feeding rate, producing substantial amounts of glucans—compounds known to support immune function and reduce blood sugar levels. This research shows that growing medicinal mushrooms in controlled bioreactors could be much more efficient and faster than traditional farming methods.

Acid Phosphatase Produced by Trichoderma harzianum in Solid Fermentation Using Millet

mycolabadmin

Researchers used a fungus called Trichoderma harzianum grown on millet grain to produce phosphatase enzymes, which help convert unavailable phosphorus in soil into forms that plants can use. By carefully controlling the amount of millet, moisture, and fungal starter culture, they achieved significantly higher enzyme production than previous methods. This inexpensive, sustainable approach could improve soil fertility and plant growth in agriculture.

Burst agitation rate promotes sustained semicontinuous cultivation of filamentous fungi in stirred tank reactors

mycolabadmin

Scientists improved the way shiitake mushrooms are grown in fermentation tanks by using a smart agitation strategy. Instead of constant stirring, they used periodic bursts of high-speed mixing to prevent clumping while maintaining healthy fungal growth. This approach increased the amount of usable biomass produced and allowed the fermentation to run longer without interruption, making mushroom cultivation more efficient and sustainable.

Engineering Strategies for Fungal Cell Disruption in Biotechnological Applications

mycolabadmin

Fungi produce valuable products inside their cells like medicines, oils, and natural colors. However, fungal cell walls are very tough and hard to break open compared to bacteria or algae. Scientists have developed various methods to break open fungal cells, ranging from physical approaches like grinding with beads or using sound waves, to gentler chemical and enzymatic methods. The best method depends on the type of fungus, what product you want to extract, and how much you need to make.

Edible mycelium as proliferation and differentiation support for anchorage-dependent animal cells in cultivated meat production

mycolabadmin

Scientists developed a new technology using edible mushroom mycelium (the root-like structure of fungi) as a scaffold to grow animal muscle cells for cultivated meat production. They tested different fungal species and found that mycelium from koji mold (Aspergillus oryzae) worked best for supporting cell growth and maturation. Unlike current plastic microcarriers that must be removed from the final product, these edible carriers can be incorporated directly into the meat, adding nutritional value and reducing waste.

Submerged Fermentation of Rhizopus sp. for l-asparaginase Production in Lymphoma Therapy

mycolabadmin

Researchers developed a new way to produce an anti-cancer enzyme called L-asparaginase using a fungus called Rhizopus, which could offer a safer alternative to current bacterial sources. They designed and tested a special bioreactor system that allows the fungus to grow as a biofilm, significantly increasing enzyme production. The system achieved enzyme activity levels much higher than previous laboratory methods, suggesting it could be scaled up for industrial pharmaceutical production.

Filamentous fungal pellets as versatile platforms for cell immobilization: developments to date and future perspectives

mycolabadmin

Filamentous fungi, commonly known as molds, can be grown into small spherical structures called pellets that act as excellent platforms for attaching and growing various types of cells. These fungal pellets are sustainable, biodegradable alternatives to synthetic materials and can support different cell types for applications ranging from producing cultivated meat to treating wastewater. The porous structure of fungal pellets allows cells to attach and grow while maintaining the ability to transfer nutrients and oxygen efficiently.

Research Topic: bioprocess engineering