Research Topic: β-glucan

Bioinspired nano-architected chitosan-β-glucan nanocomposite as an elicitor for disease management sustainably

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Scientists created tiny engineered particles made from chitosan and β-glucan that act like alarm signals to boost plants’ natural defenses against a destructive soil fungus called Sclerotium rolfsii. These nano-particles are extremely effective at just 220-240 parts per million, far more powerful than conventional fungicides which require 2000 ppm. The particles work by damaging the fungus’s cells directly while also triggering the plant’s immune system, offering farmers a sustainable alternative to chemical pesticides.

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Evaluation of Immune Modulation by β-1,3; 1,6 D-Glucan Derived from Ganoderma lucidum in Healthy Adult Volunteers, A Randomized Controlled Trial

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A study tested whether a supplement made from Reishi mushroom could boost immune system function in healthy adults. Over 84 days, people taking the Reishi β-glucan supplement showed significant improvements in immune cells and antibodies compared to those taking a placebo. The supplement was safe and well-tolerated with no negative side effects, suggesting it may help strengthen the body’s natural defenses against infections.

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From Nature to Design: Tailoring Pure Mycelial Materials for the Needs of Tomorrow

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Scientists are developing new materials made from mushroom mycelium that could replace leather, foam, and plastic products. These fungal-based materials grow on simple agricultural waste, are completely biodegradable, and have a much smaller environmental footprint than traditional materials. Companies like MycoWorks are already producing mycelium leather for major fashion brands, showing this technology is moving from laboratories into real products.

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Pathogenic mucorales: Deciphering their cell wall polysaccharidome and immunostimulatory potential

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Scientists studied three types of dangerous fungi that cause serious infections in people with weak immune systems. They looked at the outer coating of these fungi cells, which is what the body’s immune system first encounters during infection. They found that this coating contains multiple types of sugar-like substances that trigger strong inflammatory responses in immune cells. Understanding these fungi better could help develop better treatments for these serious infections.

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Delivery of Phenolic Compounds, Peptides and β-Glucan to the Gastrointestinal Tract by Incorporating Dietary Fibre-Rich Mushrooms into Sorghum Biscuits

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This study examined how adding mushroom powder to sorghum biscuits affects the availability of beneficial compounds in our digestive system. Using laboratory simulations of stomach and intestinal digestion, researchers found that mushroom-enriched biscuits released more phenolic compounds with antioxidant properties throughout the digestive tract. Importantly, the mushroom fiber helped carry beneficial β-glucan compounds to the colon, where they can be fermented by gut bacteria to produce health-promoting compounds.

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Fermentation With Pleurotus Ostreatus Enhances the Prebiotic Properties of Germinated Riceberry Rice

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This research shows that black-purple Riceberry rice can be made healthier by sprouting it and then fermenting it with oyster mushroom mycelium. The resulting product contains beneficial compounds called GABA and β-glucan that help healthy gut bacteria grow while preventing harmful bacteria like E. coli. This improved rice product could be used in foods for elderly people to support digestive and overall health.

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