therapeutic action: voriconazole therapy

Successful Management of Spondylodiscitis Caused by Aspergillus nidulans: A Case Report and Literature Review

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A 59-year-old patient with lymphoma developed a serious fungal spine infection caused by Aspergillus nidulans, a rare mold. The infection was diagnosed using imaging, fungal cultures, and laboratory testing. The patient was successfully treated with a 6-month course of the antifungal drug voriconazole without requiring surgery. This case is notable because it represents the first successful treatment of this extremely rare infection in a cancer patient.

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Spectrum of Fungal Infections in Continuous Ambulatory Peritoneal Dialysis: A 20-Year Retrospective Study From a Tertiary Care Center

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This study examined fungal infections in patients undergoing continuous ambulatory peritoneal dialysis (CAPD) over 20 years at a major Indian hospital. Researchers identified various fungal species causing peritonitis, with Candida species being most common, but discovered increasingly rare fungi involved in these infections. The study found that proper identification of the specific fungus and testing for drug resistance is crucial for effective treatment, typically involving catheter removal and targeted antifungal medications.

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Geotrichosis Due to Magnusiomyces capitatus: A Severe Emerging Invasive Fungal Disease

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A 71-year-old man with cancer undergoing chemotherapy developed a rare and serious fungal blood infection caused by Magnusiomyces capitatus. Despite treatment with antifungal medications, the infection spread throughout his body and he died 10 days after admission. This case highlights how some fungi can resist common antifungal drugs and the importance of quickly identifying the exact type of fungus causing an infection to choose the right treatment.

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The 2024 International Society for Human and Animal Mycology (ISHAM)-ABPA working group guidelines: Transforming diagnosis and management of ABPA

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Allergic bronchopulmonary aspergillosis (ABPA) is a serious lung condition that develops when people with asthma have an allergic reaction to Aspergillus fungus. New international guidelines now provide better ways to diagnose and treat this condition, making it easier for doctors to identify ABPA early and prescribe the right treatment to prevent serious lung damage like bronchiectasis.

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Spectrum of Fungal Infections in Continuous Ambulatory Peritoneal Dialysis: A 20-Year Retrospective Study From a Tertiary Care Center

mycolabadmin

This study examined fungal infections in patients undergoing continuous ambulatory peritoneal dialysis (CAPD) over 20 years at an Indian medical center. Researchers found that yeast infections, particularly Candida tropicalis, were more common than mold infections, with Aspergillus flavus being the most frequent mold. The study identified several rare and emerging fungi causing these serious infections and tested their susceptibility to antifungal medications. Results show that removing the dialysis catheter combined with appropriate antifungal treatment is crucial for patient survival.

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