therapeutic action: voriconazole eye drops

Fungal Keratitis Caused by Humicola sardiniae

A 78-year-old man developed a serious fungal eye infection caused by Humicola sardiniae, a fungus rarely seen in humans. The infection was difficult to treat because the fungus was resistant to most antifungal medications, and continued use of steroid eye drops worsened the condition. After switching to appropriate antifungal treatment and stopping the steroids, the patient’s cornea eventually healed over four months, though this was the first documented case of this particular fungus infecting a human.

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Fusarium Corneal Abscess: A Case Report

A healthy 20-year-old man developed a serious fungal eye infection caused by Fusarium, a soil fungus, despite having no typical risk factors like eye injury or contact lens wear. Doctors diagnosed the infection through laboratory tests showing fungal filaments and growing the organism in culture. The patient required multiple treatments including antifungal eye drops, injections directly into the cornea, and a graft from amniotic membrane (placenta tissue) to save his vision. The case demonstrates that fungal eye infections can occasionally occur in completely healthy people without obvious causes.

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