therapeutic action: virulence factor inhibition

New Strategies to Combat Human Fungal Infections

Fungal infections are becoming a major global health threat, causing millions of deaths annually. This research collection presents new and improved ways to treat these infections, including natural compounds like chitosan, beneficial bacteria, new drug combinations, and tests to better understand which treatments work best. The papers showcase innovative approaches beyond traditional antifungal medications to help combat resistant infections.

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Antimicrobial and Antifungal Activities of Proline-Based 2,5-Diketopiperazines Occurring in Food and Beverages and Their Synergism with Lactic Acid

Researchers synthesized special cyclic peptides called 2,5-diketopiperazines (found naturally in fermented foods like bread and cheese) and tested their ability to kill harmful molds and bacteria. When combined with lactic acid (a natural preservative), these compounds worked extremely well together, achieving nearly complete mold inhibition. This research suggests that using special starter cultures that naturally produce these compounds could help keep food fresh longer without artificial preservatives.

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