This research explores how a specific fungal gene called FoNPS6 helps the watermelon-wilt-causing fungus Fusarium oxysporum attack plants. Scientists deleted this gene and found that mutant fungi were much less aggressive, couldn’t handle stress well, and struggled to penetrate plant roots. When the gene was restored, the fungi regained full virulence. The study reveals that FoNPS6 helps the fungus absorb iron and break down plant defense chemicals.