Women with persistent abnormal uterine bleeding often undergo extensive testing without finding a cause. This study discovered that fungal infections, caused by Candida species, may be responsible for about 12% of such cases. The researchers found that direct sampling of the uterine lining is essential for diagnosis since surface vaginal cultures miss these infections. Treatment with an antifungal medication called voriconazole combined with surgical cleaning of the uterus proved effective in resolving the condition.