therapeutic action: terbinafine efficacy

Disseminated subcutaneous sporotrichosis in an immunocompetent patient: A case report and a systematic literature review

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A 74-year-old man developed multiple infected lumps on his arm, wrist, and finger months after being injured by a tree branch. Doctors identified the infection as sporotrichosis caused by a fungus called Sporothrix schenckii using advanced genetic testing. He was successfully treated with itraconazole tablets for several months and completely recovered. This case is unusual because sporotrichosis typically affects people with weakened immune systems, but this patient had a normal immune system.

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Successful management of Lomentospora prolificans septic arthritis and osteomyelitis in an immunocompetent child: A case report

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A 3-year-old healthy child developed a serious fungal bone and joint infection in the elbow after surgery to repair a broken arm bone. The fungus, called Lomentospora prolificans, is extremely resistant to most medications and can lead to limb amputation. Doctors saved the child’s arm by combining multiple approaches: repeated surgeries to clean out infected tissue, three different antifungal medications taken together, special antibiotic-loaded bone cement placed in the elbow, and antiseptic wound washing. After six months of treatment, the infection was cured and the child could use their arm again.

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