therapeutic action: suppression of fungal growth

Impact of Oxalic Acid Consumption and pH on the In Vitro Biological Control of Oxalogenic Phytopathogen Sclerotinia sclerotiorum

This research shows how bacteria can protect crops from a destructive fungus called Sclerotinia sclerotiorum. While scientists previously thought the bacteria worked by eating the toxic acid produced by the fungus, this study reveals that the bacteria also make the environment more alkaline (less acidic), which the fungus cannot tolerate. The combination of both effects—consuming the acid and changing the pH—is what actually stops the fungus from growing and damaging crops.

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Study of the antagonistic relationship between gene expression biofilm of Aspergillus niger and Staphylococcus aureus that cause otomycosis

Researchers studied how bacteria (S. aureus) and fungi (A. niger) interact when both infect the ear canal, a condition called otomycosis. They found that bacteria significantly suppress the fungus’s ability to form protective biofilms by reducing the expression of genes needed for fungal growth. This antagonistic relationship suggests that mixed infections might actually be easier to treat than pure fungal infections, offering new insights for managing ear infections.

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