stress response regulation

Two Subunits of the Rpd3 Histone Deacetylase Complex of Cochliobolus heterostrophus Are Essential for Nitrosative Stress Response and Virulence, and Interact With Stress-Response Regulators ChHog1 and ChCrz1

mycolabadmin

Scientists discovered that two proteins called ChPho23 and ChSds3 help a fungus that causes corn disease survive attacks by the plant’s immune system. These proteins work together with other cellular signals to help the fungus protect itself from harmful nitrogen-based compounds. When these proteins are removed, the fungus becomes weaker and less able to infect corn plants, suggesting these proteins could be potential targets for developing new fungicides.

Early changes in microRNA expression in Arabidopsis plants infected with the fungal pathogen Fusarium graminearum

mycolabadmin

Researchers studied how Arabidopsis plants respond to infection by the fungus Fusarium graminearum by examining changes in small RNA molecules called microRNAs. They found that the plant activates specific microRNAs early in infection, even before visible disease symptoms appear. Two particularly important microRNAs, miR855 and miR826a, were identified as potential key regulators of the plant’s defense response. These findings could help scientists develop crop varieties with improved resistance to fungal diseases that cause significant agricultural losses worldwide.

Low temperature, mechanical wound, and exogenous salicylic acid (SA) can stimulate the SA signaling molecule as well as its downstream pathway and the formation of fruiting bodies in Flammulina filiformis

mycolabadmin

Researchers studied how cooling, physical damage, and a plant hormone called salicylic acid can trigger fruiting body formation in an edible mushroom called Flammulina filiformis. They discovered that these treatments activate specific genes in the mushroom that control fruit production. This research helps explain why mushroom farmers use these methods and could improve mushroom cultivation efficiency.

The protein kinases family in fungi: adaptability, virulence and conservation between species

mycolabadmin

Protein kinases are cellular ‘switches’ that help fungi survive harsh conditions by regulating how cells make proteins and adapt to stress. A particularly important kinase called GCN2 acts as a sensor that detects when fungi lack amino acids, triggering a survival response that helps the fungus adapt and maintain pathogenicity. This review shows how understanding GCN2 could help scientists develop new antifungal drugs to treat fungal infections.

therapeutic action: stress response regulation

Two Subunits of the Rpd3 Histone Deacetylase Complex of Cochliobolus heterostrophus Are Essential for Nitrosative Stress Response and Virulence, and Interact With Stress-Response Regulators ChHog1 and ChCrz1

Early changes in microRNA expression in Arabidopsis plants infected with the fungal pathogen Fusarium graminearum

Low temperature, mechanical wound, and exogenous salicylic acid (SA) can stimulate the SA signaling molecule as well as its downstream pathway and the formation of fruiting bodies in Flammulina filiformis

The protein kinases family in fungi: adaptability, virulence and conservation between species