therapeutic action: Stress resistance

Comparative Metabolite Profiling Between Cordyceps sinensis and Other Cordyceps by Untargeted UHPLC-MS/MS

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This research compares the chemical compounds found in authentic Cordyceps sinensis with four similar but different Cordyceps species to identify which ones are real. Using advanced laboratory techniques, scientists detected thousands of chemical differences between the species. They found that genuine C. sinensis contains higher levels of specific beneficial compounds like nucleosides and certain fatty acids. These findings help consumers and merchants distinguish authentic Cordyceps from counterfeit products and lower-quality substitutes.

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L-gulono-γ-lactone Oxidase, the Key Enzyme for L-Ascorbic Acid Biosynthesis

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Vitamin C (ascorbic acid) is essential for human health, protecting against disease and supporting numerous body functions. However, humans cannot make their own vitamin C because we lack a functional GULO enzyme gene. This review examines how different organisms produce vitamin C, where these enzymes work in cells, and recent discoveries showing that a simplified version of the enzyme can still work effectively, which could help improve vitamin C production in engineered plants.

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Is Cryptococcus neoformans a pleomorphic fungus?

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Researchers have discovered that Cryptococcus neoformans, a dangerous fungus that causes serious infections, is actually much more shape-shifting than previously thought. Instead of existing as just one simple budding yeast form, the fungus can transform into several different cell types including large ‘titan cells’ and small ‘seed cells,’ each with different characteristics that help it survive and spread in the body. These different forms have distinct genetic programs and can evade the immune system in different ways, making the infection harder to treat. This discovery fundamentally changes how scientists understand this pathogen and could lead to new treatment strategies.

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Local Fungi Promote Plant Growth by Positively Affecting Rhizosphere Metabolites to Drive Beneficial Microbial Assembly

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Researchers tested local fungal species from the Qinghai-Tibet Plateau to help plants grow in damaged mining areas at extremely high altitudes. The local fungi were more effective than commercial bacterial products at promoting plant growth and creating healthy soil microbiomes. These fungi work by producing special chemicals that attract beneficial microorganisms while preventing harmful fungi from growing, making them ideal for restoring ecosystems in cold, high-altitude mining regions.

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Composition and Biodiversity of Culturable Endophytic Fungi in the Roots of Alpine Medicinal Plants in Xinjiang, China

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Scientists studied special fungi that live inside the roots of two rare alpine medicinal plants found in China’s high mountains. They discovered that these plants host over 400 different types of fungi, including a special type called dark septate fungi that make up about half of all the fungi found. Different plant species and different mountain locations had different combinations of fungi, suggesting these fungi help the plants survive in the harsh, cold mountain environment.

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