therapeutic action: regulation of salicylic acid production

A broadly conserved fungal chorismate mutase targets the plant shikimate pathway to regulate salicylic acid production and other secondary metabolites

Fungal pathogens produce proteins called effectors that help them infect plants. This study discovered that a fungus called Sclerotinia sclerotiorum produces an effector that enters plant cells and travels to chloroplasts. Unlike similar effectors in other fungi, this protein increases the production of salicylic acid, a plant defense hormone, while reducing other protective compounds. This creates conditions favorable for the fungus to establish infection.

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