therapeutic action: Reduction of fungal pathogenicity

Molecular and Biological Characterization of an Isolate of Fusarium graminearum dsRNA mycovirus 4 (FgV4) from a New Host Fusarium pseudograminearum

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Scientists discovered a virus that infects the fungus responsible for wheat crown rot disease. When this virus infects the fungus, it slows down the fungus’s growth and reduces its ability to cause disease in wheat plants. This finding suggests the virus could potentially be used as a natural biological control method to protect wheat crops from crown rot disease, offering an environmentally friendly alternative to chemical fungicides.

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In vitro activity of seven antifungal agents against Fusarium oxysporum and expression of related regulatory genes

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Researchers tested seven different antifungal medications to find the best treatment for a fungal disease that damages corn crops. Epoxiconazole worked best as a single treatment, but combining pyraclostrobin and difenoconazole together was even more effective. These medications work by interfering with the fungus’s ability to survive and infect corn, making them promising options for protecting corn crops.

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Argonaute1-Dependent LtmilR2 Negatively Regulated Infection of Lasiodiplodia theobromae by Targeting a Guanine Nucleotide Exchange Factor in RAS Signalling

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Scientists discovered a tiny regulatory RNA molecule called LtmilR2 in a fungus that causes grape disease. This molecule naturally suppresses the fungus’s ability to cause infection by shutting down a gene called LtRASGEF. When researchers delivered LtmilR2 using specially designed nanoparticles, it successfully stopped the fungus from growing. This discovery could lead to a new type of biological fungicide for protecting grapes and vineyards.

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