therapeutic action: reduced disease symptoms through HIGS

A GDP-mannose-1-phosphate guanylyltransferase as a potential HIGS target against Sclerotinia sclerotiorum

Scientists identified a critical fungal protein called SsMPG2 that helps the plant disease-causing fungus Sclerotinia sclerotiorum infect crops and survive. When this protein is silenced using genetic engineering techniques, plants become resistant to the fungus. The research shows this protein is important in many plant-pathogenic fungi, making it a promising target for developing disease-resistant crops through genetic modification.

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