therapeutic action: psychological flexibility

Navigating groundlessness: An interview study on dealing with ontological shock and existential distress following psychedelic experiences

People who use psychedelic substances like psilocybin or LSD sometimes experience profound changes in how they understand reality that can be distressing and last for months or years. This study interviewed 26 people who went through such difficult experiences and found that what helped them most was practicing grounding techniques (like yoga, spending time in nature, and creative activities), talking about their experiences with others, and learning to accept their new perspectives. The research shows that while these experiences can be challenging, people can recover and grow from them with the right support and practices.

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A clinical protocol for group-based ketamine-assisted therapy in a community of practice: the Roots To Thrive model

The Roots to Thrive ketamine-assisted therapy program is a 12-week group treatment that combines ketamine sessions with weekly group meetings, somatic practices, and emotional support. The program integrates both Western clinical approaches and Indigenous wisdom, treating depression, anxiety, and PTSD in groups of 20-40 participants. Over 750 people have participated with significant improvements in mental health symptoms and life functioning, demonstrating that this group-based approach is both safe and effective.

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Safety, feasibility, tolerability, and clinical effects of repeated psilocybin dosing combined with non-directive support in the treatment of obsessive-compulsive disorder: protocol for a randomized, waitlist-controlled trial with blinded ratings

This clinical trial is investigating whether psilocybin (a psychoactive compound found in certain mushrooms) combined with supportive counseling can help people with treatment-resistant obsessive-compulsive disorder. Researchers will give participants two doses of psilocybin while providing non-directive psychological support to help them process their experiences. The study aims to determine whether this approach is safe, tolerable, and effective at reducing OCD symptoms, and to understand the psychological mechanisms that might explain how it works.

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