therapeutic action: Potential target identification for antifungal development

Characterization of ORF19.7608 (PPP1), a biofilm-induced gene of Candida albicans

Researchers studied a gene called PPP1 in Candida albicans, a common fungal infection in hospitals. They found that this gene is highly active when the fungus forms protective biofilms on medical devices like catheters. Although the protein appears in a distinctive spotted pattern only during biofilm formation, removing this gene did not prevent biofilm formation or affect how the fungus responds to stress or antifungal drugs.

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