therapeutic action: Potential neuroplasticity promotion

Psychedelics and the treatment of eating disorders: considerations for future research and practice

As researchers explore using psychedelic drugs like psilocybin to treat eating disorders, this article outlines important safety considerations and ethical guidelines needed before widespread use. While some early trials show promise, significant concerns exist including physiological risks (heart problems, nausea), psychological challenges, potential for therapist misconduct, and medication interactions. The authors recommend rigorous research designs, better inclusion of diverse populations, and careful integration of psychedelics with proven eating disorder treatments.

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Investigating the Potential of Psilocybin for Compulsive Eating in a Rat Model of Binge Eating

Researchers tested whether psilocybin, a psychedelic compound from magic mushrooms, could help reduce compulsive eating in rats bred to binge eat high-fat, high-sugar foods. Using a fear-conditioning experiment, they found that a single dose of psilocybin did not reduce the rats’ compulsive eating behavior at the dosage tested. However, the treatment may have affected fear-related freezing responses, suggesting psilocybin might influence brain circuits involved in learning and memory.

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