therapeutic action: Potential for preventing OTA production through genetic modification

Impact of OTAbZIP on Ochratoxin A production, mycelium growth and pathogenicity of Aspergillus westerdijkiae under water activity stress

Researchers studied how a specific gene (OTAbZIP) in a fungus called Aspergillus westerdijkiae controls the production of ochratoxin A, a poisonous substance that can contaminate food. By removing this gene, scientists found that the fungus could no longer produce the toxin, even when exposed to different moisture levels. This discovery could help prevent food contamination with this dangerous mycotoxin and protect human health.

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