oxidative stress reduction – Page 2

Research Progress on the Mechanisms of Polysaccharides against Gastric Cancer

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This review explores how natural polysaccharides from mushrooms, seaweed, plants, and traditional herbs can fight gastric cancer. These compounds work by triggering cancer cell death, stopping tumor growth, and boosting the body’s immune system. Unlike conventional chemotherapy drugs that cause serious side effects, these natural polysaccharides offer a safer alternative that can work alongside existing treatments to improve patient survival.

Impact of Cordyceps sinensis on coronary computed tomography angiography image quality and renal function in a beagle model of renal impairment

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This study tested whether a traditional mushroom supplement called Cordyceps sinensis could protect kidney function in dogs undergoing heart imaging tests that use contrast dye. Researchers found that dogs receiving Cordyceps sinensis combined with lower doses of contrast dye maintained good image quality while showing better kidney function afterward compared to controls receiving conventional contrast doses without the supplement. Advanced imaging techniques confirmed that Cordyceps sinensis helped protect kidney tissue from damage caused by the contrast material.

Potential of Wormwood and Oak Bark-Based Supplement in Health Improvement of Nosema ceranae-Infected Honey Bees

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This study tested a natural dietary supplement made from wormwood and oak bark on honey bees infected with Nosema ceranae, a parasite that weakens bee colonies. The supplement significantly improved bee survival and reduced parasite levels, regardless of when it was given. It also reduced harmful oxidative stress caused by the infection. While it didn’t boost immune genes as strongly as some other treatments, its plant-based nature and consistent effectiveness make it a promising tool for beekeepers.

The Therapeutic Effect and Mechanism of Traditional Chinese Medicine in Type 2 Diabetes Mellitus and Its Complications

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Traditional Chinese Medicine uses various herbs and plant compounds to treat Type 2 diabetes by improving how the body controls blood sugar and protects the pancreas. Many common TCM herbs like ginseng, rehmannia, and coptis work through natural mechanisms that reduce inflammation, protect cells from damage, and improve how the body uses insulin. Research shows TCM may also help prevent or reduce diabetes-related complications affecting the eyes, kidneys, and nerves. These herbal treatments offer potential benefits with fewer side effects compared to conventional medications.

Inonotus obliquus aqueous extract prevents histopathological alterations in liver induced by environmental toxicant Microcystin

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This research shows that Chaga mushroom extract can protect the liver from damage caused by microcystin, a toxic chemical produced by cyanobacteria in water. When mice were exposed to microcystin, their livers became damaged, but treating them with Chaga mushroom extract restored normal liver function and prevented cell death. The study suggests Chaga mushroom could be used as a natural supplement to prevent liver toxicity from environmental pollutants.

Polyphenolic Hispolon Derived from Medicinal Mushrooms of the Inonotus and Phellinus Genera Promotes Wound Healing in Hyperglycemia-Induced Impairments

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Researchers tested a natural compound called hispolon, extracted from medicinal mushrooms, to see if it could help heal wounds in diabetic patients. Using both laboratory cells and diabetic rats, they found that hispolon successfully reduced cell damage caused by high blood sugar, improved wound closure, and promoted healthy tissue growth. The compound worked as well as an existing diabetic wound cream and showed no harmful side effects, suggesting it could become a new natural treatment option for diabetic wound complications.

Selenoproteins in Health

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Selenium is an essential nutrient that your body needs for healthy immune function, protection against oxidative stress, and proper thyroid function. While you can get selenium from foods like grains, vegetables, nuts, and animal products, the amount available depends on soil selenium levels in the regions where food is grown. Organic forms of selenium from food sources are more effective and safer than inorganic supplements, providing better protection against diseases like cancer, diabetes, and cardiovascular conditions.

Integrated Transcriptomics and Metabolomics Provide Insight into Degeneration-Related Molecular Mechanisms of Morchella importuna During Repeated Subculturing

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Morel mushrooms (Morchella importuna) lose quality when repeatedly grown from cultured samples, a process called strain degeneration. Scientists found that degenerated strains have lower levels of beneficial compounds called flavonoids, which normally protect mushroom cells from damage. By studying gene expression and metabolite changes, researchers identified a specific gene responsible for making these protective flavonoids, which becomes less active in degenerated strains. This research suggests that avoiding frequent reculturing and maintaining cold storage or adding antioxidants could help preserve healthy morel mushroom strains.

Effects of Isaria cateniannulata on the colonization process and enzyme activity of Fagopyrum tataricum seeds during germination

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Researchers discovered that a special fungus called Isaria cateniannulata can successfully colonize buckwheat seeds and promote their germination. When seeds are treated with this fungus, the resulting plants produce more protective enzymes that reduce damage from oxidative stress. Additionally, plants grown from fungus-treated seeds are more resistant to spider mites, laying fewer eggs and reducing pest populations. This discovery offers a natural, biotechnology-based approach to improve seed germination and pest control in buckwheat farming.

Polysorbate 80 Differentially Impacts Erinacine Production Profiles in Submerged Cultures of Hericium

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Lion’s mane mushroom and related Hericium species produce beneficial compounds called erinacines that may protect the brain and help with neurological conditions. This study tested how adding glucose and a substance called polysorbate 80 to mushroom cultures affects erinacine production. Interestingly, while polysorbate 80 helped mushrooms grow more, it reduced erinacine levels in most strains, though effects varied by species. The findings could help cultivators choose conditions to grow mushrooms enriched with specific beneficial compounds.

therapeutic action: oxidative stress reduction