therapeutic action: oxidative stress mitigation

Ultrasound-assisted extraction of neuroprotective antioxidants from Ganoderma lucidum

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This research studied how to best extract healing compounds from the reishi mushroom (Ganoderma lucidum), an important traditional Chinese medicine. Using advanced extraction techniques and computer modeling, scientists identified optimal conditions that doubled the amount of beneficial antioxidants obtained compared to conventional methods. They then tested these extracts on nerve cells in the laboratory, demonstrating that the extracts effectively protected cells from oxidative damage and injury.

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Biocontrol of Fusarium solani: Antifungal Activity of Chitosan and Induction of Defence Enzymes

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Chitosan, a natural substance made from shrimp and crab shells, effectively protects tomato plants from a dangerous fungal disease called Fusarium solani root rot. When applied to plants, chitosan directly damages the fungus and simultaneously strengthens the plant’s own defence systems through increased enzyme activity. This makes chitosan a safer, more sustainable alternative to conventional chemical fungicides while also promoting better plant growth.

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Arbuscular mycorrhizal networks—A climate-smart blueprint for agriculture

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Arbuscular mycorrhizal fungi are beneficial organisms that form partnerships with plant roots to improve crop health and productivity without relying heavily on synthetic chemicals. These fungal networks enhance soil health, help plants survive droughts and diseases, improve nutrient absorption, and redistribute water through the soil. By using proper farming practices like crop diversification and fungal inoculants, farmers can harness these natural networks to increase yields while reducing fertilizer costs and environmental pollution.

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Molecular Regulation of Carotenoid Accumulation Enhanced by Oxidative Stress in the Food Industrial Strain Blakeslea trispora

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Researchers studied how stressful conditions can make a fungus called Blakeslea trispora produce more carotenoids, which are natural pigments used to color food products. When exposed to chemical stressors like rose bengal or hydrogen peroxide, the fungus produced significantly more carotenoids – up to four times more in some cases. The study identified specific genes and cellular pathways responsible for this increased production, which could help food companies produce natural food colorants more efficiently.

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Arsenic Stress Resistance in the Endophytic Fungus Cladosporium cladosporioides: Physiological and Transcriptomic Insights into Heavy Metal Detoxification

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Researchers discovered a special fungus called Cladosporium cladosporioides living inside the roots of Gentiana yunnanensis, a traditional Chinese medicinal herb. This fungus is remarkably good at tolerating and neutralizing arsenic, a toxic heavy metal found in contaminated soils. The fungus uses multiple strategies to protect itself from arsenic damage, including moving the arsenic to its cell walls, converting it into less toxic forms, and activating protective defense systems.

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Adaptive Responses in High-Radiation Environments: Insights From Chernobyl Wildlife and Ramsar Residents

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Animals and people living in highly radioactive areas have developed natural adaptations to survive and thrive despite dangerous radiation levels. Frogs in Chernobyl have evolved darker skin that helps protect against radiation, while residents of Ramsar, Iran have developed enhanced DNA repair abilities over generations. These discoveries challenge traditional beliefs about radiation dangers and suggest that life can adapt to extreme environmental stressors in unexpected ways.

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