therapeutic action: oxidative stress induction

Comparative Study and Transcriptomic Analysis on the Antifungal Mechanism of Ag Nanoparticles and Nanowires Against Trichosporon asahii

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Researchers compared two types of tiny silver particles (nanoparticles and nanowires) as potential treatments for a dangerous fungal infection caused by Trichosporon asahii. Silver nanowires were found to be more effective than nanoparticles at killing the fungus by damaging its cell membranes and disrupting its energy production. The study identified 15 key genes involved in how silver nanowires attack the fungus, suggesting these nanomaterials could become useful alternatives to traditional antifungal drugs.

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Essential Oils as an Antifungal Alternative to Control Several Species of Fungi Isolated from Musa paradisiaca: Part III

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This research tested how essential oils from common cooking herbs like oregano, thyme, and cinnamon can prevent fungal diseases on bananas after harvest. Scientists identified five different fungi causing banana rot, then tested six plant-based oils at different strengths to see which ones worked best. Thyme oil was most effective, completely stopping fungal growth at the highest concentration tested. These natural oils could replace harsh chemical fungicides while being safer for people and the environment.

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Graphene nanomaterials: A new frontier in preventing respiratory fungal infections

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Graphene nanomaterials, especially nano-graphene oxide, show promise as new treatments for serious lung fungal infections that particularly threaten people with weakened immune systems. These tiny materials work by generating damaging reactive oxygen species that kill fungal cells and prevent biofilm formation. Unlike traditional antifungal drugs, nano-graphene oxide can be delivered directly to infected lung tissue via inhalation, delivering medicine exactly where needed while reducing harmful side effects throughout the body.

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Deoxynucleosides as promising antimicrobial agents against foodborne pathogens and their applications in food and contact material surfaces

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Researchers found that two nucleoside compounds (ddA and FdCyd) can effectively kill harmful bacteria like Vibrio and Salmonella that form slimy biofilms on seafood and food preparation surfaces. These compounds work by damaging bacterial cell membranes and preventing bacteria from communicating with each other. When combined with a food additive already used in the meat industry, these nucleosides become even more effective at much lower doses, potentially making food safer while reducing residual chemical effects.

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Antifungal Activity of Selected Naphthoquinones and Their Synergistic Combination with Amphotericin B Against Cryptococcus neoformans H99

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Scientists tested five synthetic compounds called naphthoquinones to see if they could fight a serious fungal infection called cryptococcosis. They found that one compound called 2-MNQ worked well against the fungus and was even more effective when combined with a standard antifungal drug (amphotericin B). The combination was strong enough to potentially allow lower doses of the existing drug, which could reduce side effects while improving treatment outcomes.

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Graphene nanomaterials: A new frontier in preventing respiratory fungal infections

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Scientists are exploring nano-graphene oxide, a microscopic material made from graphene, as a new treatment for serious lung fungal infections. These tiny particles can kill fungal cells through multiple mechanisms and deliver antifungal drugs directly to infection sites while reducing harmful side effects. Researchers found that graphene oxide can be combined with existing antifungal medications to make them work better and even help overcome drug-resistant fungal infections.

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