Neurotrophic activity

Hericioic Acids A–G and Hericiofuranoic Acid; Neurotrophic Agents from Cultures of the European Mushroom Hericium flagellum

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Researchers isolated eight new bioactive compounds from a rare European mushroom species called Hericium flagellum. These compounds showed promising ability to stimulate nerve cell growth and could potentially help treat neurodegenerative diseases like Alzheimer’s and Parkinson’s. The study demonstrates that mushroom-derived natural products may offer new therapeutic approaches for conditions affecting millions of elderly people worldwide.

Polysorbate 80 Differentially Impacts Erinacine Production Profiles in Submerged Cultures of Hericium

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Lion’s mane mushroom and related Hericium species produce beneficial compounds called erinacines that may protect the brain and help with neurological conditions. This study tested how adding glucose and a substance called polysorbate 80 to mushroom cultures affects erinacine production. Interestingly, while polysorbate 80 helped mushrooms grow more, it reduced erinacine levels in most strains, though effects varied by species. The findings could help cultivators choose conditions to grow mushrooms enriched with specific beneficial compounds.

therapeutic action: Neurotrophic activity

Hericioic Acids A–G and Hericiofuranoic Acid; Neurotrophic Agents from Cultures of the European Mushroom Hericium flagellum

Polysorbate 80 Differentially Impacts Erinacine Production Profiles in Submerged Cultures of Hericium