therapeutic action: Nematicidal

Fungi: Pioneers of chemical creativity – Techniques and strategies to uncover fungal chemistry

This review explores how fungi produce remarkable chemical compounds that have been transformed into important medicines for over a century. Starting with penicillin in the 1940s, scientists have discovered dozens of fungal-derived drugs used to treat infections, prevent organ rejection, lower cholesterol, and fight cancer. Modern technology now allows researchers to discover and analyze these compounds much faster and with smaller samples than ever before.

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Recent developments of tools for genome and metabolome studies in basidiomycete fungi and their application to natural product research

Mushrooms and related fungi in the basidiomycete group produce many useful medicines and agricultural chemicals. Scientists have traditionally struggled to study these fungi because they grow slowly and have complex genomes. Recent technological breakthroughs—including faster DNA sequencing and gene-editing tools—are now making it much easier to discover and understand the helpful compounds these fungi produce, potentially leading to new medicines.

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Xenorhabdus spp.: An Overview of the Useful Facets of Mutualistic Bacteria of Entomopathogenic Nematodes

Xenorhabdus bacteria are tiny organisms that naturally live inside microscopic worms used for pest control. These bacteria produce powerful substances that can kill harmful insects, fungi, and plant-damaging worms without using toxic chemical pesticides. Scientists are discovering new types of these bacteria and their compounds, which could help create safer products for farming and disease control. This research shows these beneficial microbes could replace harmful chemicals in agriculture.

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Modern Pro-Health Applications of Medicinal Mushrooms: Insights into the Polyporaceae Family, with a Focus on Cerrena unicolor

This review explores how medicinal mushrooms, particularly Cerrena unicolor, can be used to improve health through functional foods and supplements. The mushroom contains natural compounds with powerful properties including fighting cancer cells, killing harmful bacteria and viruses, and protecting the body from oxidative stress. Research shows these mushrooms could be incorporated into dairy products and other foods to create innovative health-promoting products for consumers.

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