mycotoxin detoxification

Enhancing the Substrate Adaptability of Laccase through Ancestral Sequence Reconstruction for Applications in Mycotoxin Detoxification

mycolabadmin

Researchers used evolutionary analysis to redesign a fungal enzyme called laccase to better detoxify harmful mold toxins found in grains. The new engineered enzyme (LacANC278) can break down both aflatoxin and zearalenone toxins much more effectively than the original enzyme, and converts them into less harmful substances. This enzyme works without expensive helper chemicals and works well at room temperature, making it practical for treating contaminated corn and other grains.

Aflatoxin B1 (AFB1) biodegradation by a lignolytic phenoloxidase of Trametes hirsuta

mycolabadmin

Scientists discovered that a mushroom called Trametes hirsuta produces a special enzyme that can break down aflatoxin B1, a dangerous toxin that contaminates foods like peanuts, corn, and nuts. This enzyme is unique because it works without needing additional chemicals as helpers, making it practical for real-world use. The enzyme successfully degraded 77.9% of the toxin under simple conditions, and researchers suggest it could be applied directly to contaminated food surfaces as a safe, natural way to reduce food poisoning risks.

Pleurotus eryngii Culture Filtrate and Aqueous Extracts Alleviate Aflatoxin B1 Synthesis

mycolabadmin

This research demonstrates that extracts from oyster mushrooms (Pleurotus eryngii) can effectively prevent the production of aflatoxin B1, a highly toxic and cancer-causing substance produced by certain molds that contaminate crops like corn and wheat. The mushroom extracts work by inhibiting the toxin production by up to 94%, offering a natural, environmentally-friendly alternative to chemical pesticides. The study suggests that compounds in mushrooms, including special sugars and enzymes, may help protect food supplies from this dangerous contamination, which is becoming increasingly important as climate change creates more favorable conditions for mold growth.

Patulin Biodegradation by Rhodosporidiobolus ruineniae and Meyerozyma guilliermondii Isolated From Fruits

mycolabadmin

Patulin is a dangerous toxin produced by molds that grow on apples and peaches, posing serious health risks to consumers. Researchers isolated two yeast species from fruits that can effectively break down patulin into a less toxic compound called (E)-ascladiol. The yeasts work by using enzymes inside their cells to degrade the toxin, and this biological approach could be used to safely remove patulin from contaminated fruits and fruit products.

Lactic acid bacteria: beyond fermentation to bio-protection against fungal spoilage and mycotoxins in food systems

mycolabadmin

Mold and fungal toxins spoil food and threaten human health, costing billions globally. While chemical preservatives work, many consumers want natural alternatives. Lactic acid bacteria (the same organisms used in yogurt production) produce natural antimicrobial compounds that can prevent mold growth and neutralize harmful toxins, offering a safer, more natural way to keep food fresh longer.

Removal of Aflatoxin B1 by Edible Mushroom-Forming Fungi and Its Mechanism

mycolabadmin

This research discovered that edible mushroom varieties, particularly Bjerkandera adusta, can remove harmful aflatoxin B1 poison from food and animal feed. The mushroom fungi work by binding the toxin to their cell structures, acting like a sponge that soaks up the dangerous chemical. This natural method is safer and more practical than chemical or heat-based approaches because it doesn’t damage the nutritional value of food while making it safer to eat.

Biocontrol of Aflatoxigenic Maize Molds Using Lactobacillus spp.-Based Formulations

mycolabadmin

This study shows that beneficial bacteria called Lactobacillus, found in traditional fermented foods like fura and gapal, can effectively reduce dangerous mold toxins (aflatoxins) in maize. Researchers tested these bacteria on contaminated maize samples and found they could reduce fungal contamination by up to 68% and completely eliminate some toxins. This natural approach offers a safer, cheaper alternative to chemical treatments while preserving food quality and safety.

Current Approaches to Aflatoxin B1 Control in Food and Feed Safety: Detection, Inhibition, and Mitigation

mycolabadmin

Aflatoxins are poisonous substances made by certain molds that contaminate about a quarter of the world’s food supply and are known carcinogens. This review examines the latest methods for detecting these toxins (from simple lab tests to advanced smartphone-powered devices) and ways to remove or prevent them, including using beneficial bacteria and special plasma treatment. The research shows that combining multiple approaches—detection technology with biological solutions—works best for keeping our food and animal feed safe from these dangerous contaminants.

therapeutic action: mycotoxin detoxification