therapeutic action: mycelial growth inhibition

The green shield: Trichoderma’s role in sustainable agriculture against soil-borne fungal threats

This study examined how a beneficial fungus called Trichoderma can protect crops from harmful soil fungi without using chemical pesticides. Researchers isolated Trichoderma from soil in Kashmir and tested it against 12 different disease-causing fungi. The results showed that Trichoderma effectively stopped the growth of harmful fungi both through direct contact and through compounds it produces. This natural approach could help farmers grow healthier crops while protecting the environment.

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An Efficient Microwave Synthesis of 3-Acyl-5-bromoindole Derivatives for Controlling Monilinia fructicola and Botrytis cinerea

Researchers created new chemical compounds based on indoles that can kill harmful fungi affecting fruit crops. These compounds were made using microwave energy, which made the synthesis faster and more efficient. Testing showed that some of these new compounds worked better at stopping fungal growth and spore germination than currently used commercial fungicides, making them promising candidates for protecting fruit crops from rot diseases.

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Pathogen identification and biological fungicides screening for Plumbago auriculata blight in China

Researchers identified a fungal pathogen (Fusarium ipomoeae) causing a serious disease in Plumbago auriculata ornamental plants in China. They tested seven biological fungicides and found that osthole was the most effective at preventing the disease. The study provides gardeners and farmers with an environmentally friendly solution to control this plant disease using a natural compound.

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Fungal inhibitory activity of sesquiterpenoids isolated from Laggera pterodonta

Researchers isolated six antifungal compounds from a traditional Chinese medicine plant called Laggera pterodonta. One compound called costic acid showed excellent ability to kill common crop-destroying fungi like P. nicotianae and F. oxysporum by damaging their cell membranes. These natural compounds could serve as safer alternatives to synthetic fungicides in agriculture, offering environmental benefits without toxic chemical residues.

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Isolation and Identification of Aspergillus spp. from Rotted Walnuts and Inhibition Mechanism of Aspergillus flavus via Cinnamon Essential Oil

Researchers collected rotted walnuts from storage in Shanxi, China and identified five types of Aspergillus fungi contaminating them, with Aspergillus flavus being the most common. They tested cinnamon essential oil as a natural antifungal treatment and found it effectively stopped fungal growth by damaging the fungi’s cell membranes and causing oxidative stress. This research suggests cinnamon essential oil could be used as a safe, natural alternative to chemical fungicides for preserving walnuts and other foods from fungal spoilage.

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Green Synthesized Copper-Oxide Nanoparticles Exhibit Antifungal Activity Against Botrytis cinerea, the Causal Agent of the Gray Mold Disease

Scientists developed tiny copper oxide particles using fungi to create a natural fungicide that fights gray mold, a disease that damages grapes and other crops worldwide. These bio-based nanoparticles work better than conventional copper fungicides, offering farmers a more environmentally friendly option. However, the particles showed some toxicity to human cells in laboratory tests, suggesting they need careful handling before field use.

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Antifungal Volatile Organic Compounds from Talaromyces purpureogenus CEF642N: Insights from One Strain Many Compounds (OSMAC) Strategy for Controlling Verticillium dahliae in Cotton

Scientists discovered that a beneficial fungus called Talaromyces purpureogenus produces natural antifungal compounds that effectively control cotton wilt disease caused by the harmful fungus Verticillium dahliae. The study identified two main compounds, 3-octanol and 2-octenal, that showed strong antifungal activity without synthetic chemicals. This research offers a promising green alternative for protecting cotton crops from one of agriculture’s major diseases while being environmentally friendly.

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Talaromyces pinophilus Strain HD25G2 as a Novel Biocontrol Agent of Fusarium culmorum, the Causal Agent of Root and Crown Rot of Soft Wheat

A fungus called Talaromyces pinophilus shows promise as a natural pest controller against Fusarium culmorum, which damages wheat crops worldwide. When applied early to wheat seeds, this beneficial fungus produces enzymes that break down the harmful fungus’s cell walls, completely preventing damage and toxin contamination. However, timing is critical—if applied too late, it can paradoxically increase toxin production, suggesting it works best as a preventative treatment before infection occurs.

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Volatile Metabolome and Transcriptomic Analysis of Kosakonia cowanii Ch1 During Competitive Interaction with Sclerotium rolfsii Reveals New Biocontrol Insights

This research demonstrates how a beneficial bacterium called Kosakonia cowanii Ch1 can fight a harmful fungus that damages crops. The bacterium produces volatile chemicals that inhibit fungal growth and shows different gene activity depending on whether these chemicals are present. When the beneficial bacteria and fungus compete together with the volatiles present, the bacteria win by producing gas bubbles and effectively stopping the fungus. These findings suggest a natural alternative to chemical fungicides for protecting crops.

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Volatile Metabolome and Transcriptomic Analysis of Kosakonia cowanii Ch1 During Competitive Interaction with Sclerotium rolfsii Reveals New Biocontrol Insights

Researchers studied how a beneficial bacterium called K. cowanii fights against a harmful soil fungus (S. rolfsii) that damages crops like chili peppers. The bacterium produces special smelly compounds (VOCs) that kill the fungus. When these compounds are present, the bacterium activates specific genes that help it produce substances to protect itself and inhibit fungal growth. This research could help farmers use natural biocontrol instead of chemical fungicides.

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