therapeutic action: mycelial growth inhibition

Volatile Organic Compounds Produced by Co-Culture of Burkholderia vietnamiensis B418 with Trichoderma harzianum T11-W Exhibits Improved Antagonistic Activities against Fungal Phytopathogens

Scientists studied how two beneficial microorganisms (a bacterium and a fungus) work together to produce compounds that kill plant-damaging fungi. When grown together, they produced more protective compounds than when grown separately, showing promise as a natural alternative to chemical fungicides for protecting crops and stored fruits from fungal diseases.

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An Efficient Microwave Synthesis of 3-Acyl-5-bromoindole Derivatives for Controlling Monilinia fructicola and Botrytis cinerea

Scientists developed new chemical compounds called indole derivatives that can kill harmful fungi that destroy fruit crops like stone fruits and grapes. These compounds were made using microwave heating, which is faster and more efficient than traditional methods. Testing showed that some of these new compounds were even better at fighting these fungal diseases than current commercial fungicides, offering promise for protecting crops in agriculture.

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Chilean Aloysia Essential Oils: A Medicinal Plant Resource for Postharvest Disease Control

Researchers tested essential oils from two Chilean herbs, Aloysia citriodora and Aloysia polystachya, against fungi that cause fruit rot after harvest. They found that oil from Aloysia citriodora, especially a compound called farnesol, effectively killed the disease-causing fungi in laboratory tests. These natural oils could replace synthetic fungicides that are becoming less effective and harmful to the environment, offering farmers a safer way to protect their fruit during storage and transport.

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In vitro antifungal activity of plant extracts against fungal pathogens of onion (Allium cepa L.) and red pepper (Capsicum annum L.) in selected districts of Western Hararghe, Ethiopia

Onion and pepper farmers in Ethiopia lose significant crops to fungal diseases, and chemical fungicides are expensive and harmful. This study tested plant extracts from garlic, neem, and African wintersweet against disease-causing fungi. Acokanthera schimperi (African wintersweet) was most effective at stopping fungal growth, offering farmers an affordable, natural, and environmentally safe alternative to chemical fungicides.

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Pathogen identification and biological fungicides screening for Plumbago auriculata blight in China

Researchers in China identified a fungal disease affecting Plumbago auriculata (cape leadwort), a popular ornamental plant. The disease was caused by Fusarium ipomoeae, a fungus that causes yellowing and death of plant tissue. Scientists tested seven biological pesticides and found that osthole, a natural compound, was most effective at controlling the fungus and preventing disease.

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An Efficient Microwave Synthesis of 3-Acyl-5-bromoindole Derivatives for Controlling Monilinia fructicola and Botrytis cinerea

Scientists created new chemical compounds based on indole structures that can kill harmful fungi that destroy fruit crops. These compounds were made more efficiently using microwave heating and tested against two major crop pathogens that cause billions of dollars in losses annually. The most promising compound (A) proved even more effective than commercial fungicides at stopping fungal growth and spore germination. This research could lead to better, safer alternatives for protecting crops from fungal diseases.

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Synthesis of zinc oxide nanoparticles using Trichoderma harzianum and its bio-efficacy on Alternaria brassicae

Scientists have developed an eco-friendly way to create zinc oxide nanoparticles using a beneficial fungus called Trichoderma harzianum. These nanoparticles effectively kill Alternaria brassicae, a fungus that damages mustard crops and can reduce yields by up to 57%. The nanoparticles work better and at lower doses than traditional chemical fungicides, making them a promising sustainable solution for farmers. This represents an important advancement in protecting crops without harming the environment.

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Antifungal effects of metabolites from Arthrinium sp. 2–65 and identification of main active ingredients

Scientists discovered that a fungus called Arthrinium sp. 2–65, found living inside a wild plant called Thymus mongolicus, produces two special compounds that can kill the fungus responsible for grey mould disease. Grey mould is a major problem for farmers worldwide, damaging crops like tomatoes, grapes, and strawberries. These newly identified compounds were tested and showed excellent effectiveness against the disease, offering a promising natural alternative to chemical pesticides that have become less effective due to resistance and environmental concerns.

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Cinchona-based liquid formulation exhibits antifungal activity through Tryptophan starvation and disruption of mitochondrial respiration in Rhizoctonia Solani

Scientists discovered that a liquid extract from Cinchona bark, which contains quinine, can effectively kill a fungus that damages rice crops. The treatment works by blocking the fungus’s ability to absorb tryptophan (an important amino acid) and damaging its energy-producing mitochondria. When tryptophan was added back to the treatment, the fungus recovered, confirming this is the main way the extract works. This natural, plant-based approach could provide an eco-friendly alternative to chemical fungicides while reducing the risk of the fungus developing resistance.

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An Efficient Microwave Synthesis of 3-Acyl-5-bromoindole Derivatives for Controlling Monilinia fructicola and Botrytis cinerea

Scientists created new chemical compounds based on indole molecules that can effectively kill two harmful fungi that destroy fruit crops. These compounds were made using microwave heating, which is faster and more efficient than traditional methods. Tests showed that some of these new compounds work even better than commercial fungicides at killing these fungi, and they may work by blocking an important energy-producing process in the fungal cells.

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