therapeutic action: mycelial damage

Antifungal mechanism of ketone volatile organic compounds against Pseudogymnoascus destructans

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Researchers discovered that two ketone compounds, 2-undecanone and 2-nonanone, effectively kill Pseudogymnoascus destructans, the fungus that causes white-nose syndrome in bats. Using advanced genetic analysis, they found these ketones work by damaging the fungus’s cell structure, disrupting its energy production, and causing DNA damage. This research provides a foundation for developing new fumigant treatments to protect bat populations from this devastating fungal disease.

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Screening microbial inhibitors of Pseudogymnoascus destructans in Northern China

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Scientists in Northern China have found bacteria living on bat skin and in cave soil that can kill the fungus responsible for white-nose syndrome, a disease devastating bat populations worldwide. These bacteria produce various antifungal compounds including volatile organic compounds that diffuse through the air and damage the fungus’s structure. By analyzing the genetic makeup of these bacteria, researchers identified specific genes responsible for producing these antifungal compounds, offering hope for developing biological control treatments that could protect bats and reduce fungal loads in cave environments.

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Antifungal activity of zinc oxide nanoparticles (ZnO NPs) on Fusarium equiseti phytopathogen isolated from tomato plant in Nepal

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Researchers in Nepal developed a natural way to fight tomato plant diseases by creating tiny zinc oxide nanoparticles from tea leaves. These nanoparticles successfully stopped the growth of a harmful fungus called Fusarium equiseti that was damaging tomato crops. Unlike chemical fungicides that can harm the environment, this eco-friendly approach damaged the fungus’s cell structures without posing risks to surrounding ecosystems, offering farmers a safer way to protect their crops.

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Complete genome analysis and antimicrobial mechanism of Bacillus velezensis GX0002980 reveals its biocontrol potential against mango anthracnose disease

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Researchers discovered a beneficial bacterium called Bacillus velezensis that can prevent mango rot caused by a destructive fungus. This bacterium produces natural antimicrobial compounds that kill the disease-causing fungus without the need for harmful chemical pesticides. When applied to mangoes, it reduced disease by 52% and extended the fruits’ shelf life, offering a safe and environmentally friendly solution for protecting mangoes after harvest.

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