therapeutic action: Lipid reduction

Ganoapplanilactone C from Ganoderma applanatum Ameliorates Metabolic Dysfunction-Associated Steatotic Liver Disease via AMPK/mTOR-Mediated Lipid Regulation in Zebrafish

Researchers found that a compound called ganoapplanilactone C from the medicinal mushroom Ganoderma applanatum can protect the liver from fat accumulation and damage caused by high-fat diets. In zebrafish studies, this compound worked better than a common cholesterol drug at reducing liver fat and improving liver health. The compound appears to work by activating a protein called AMPK that helps regulate how the body processes fats and reduces inflammation.

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The release patterns and potential prebiotic characteristics of soluble and insoluble dietary fiber-bound polyphenols from pinot noir grape pomace in vitro digestion and fermentation

This study examined how grape pomace dietary fiber and its bound polyphenols are broken down in the digestive system and colon. Researchers found that soluble fiber was particularly effective at releasing beneficial compounds that feed healthy gut bacteria and produce short-chain fatty acids important for health. The fiber types promoted beneficial bacteria like Bifidobacterium while reducing harmful bacteria, suggesting grape pomace could be a valuable ingredient in functional foods to support digestive and overall health.

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