therapeutic action: kojic acid production for cosmetic and pharmaceutical applications

The Zn(II)2-Cys6-type zinc finger protein AoKap7 is involved in the growth, oxidative stress and kojic acid synthesis in Aspergillus oryzae

Scientists studied a protein called AoKap7 in a fungus (Aspergillus oryzae) that produces kojic acid, a substance used in cosmetics and medicine. When they removed this protein, the fungus grew faster but made less kojic acid and became more vulnerable to stress. The researchers found that AoKap7 controls several genes that help the fungus protect itself from harmful molecules and produce kojic acid efficiently.

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