Itraconazole – Page 3

Prevalence of Candida and Other Yeasts in Vulvovaginal Infections during Pregnancy: A 10-Year Serbian Survey

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This study examined yeast infections in pregnant Serbian women over 10 years, finding that nearly half had vulvovaginal yeast infections. While Candida albicans remained the most common cause, other yeast species are increasingly found and can be harder to treat. The research emphasizes the importance of accurate laboratory identification of yeast species to guide proper antifungal treatment and prevent serious complications for both mother and newborn.

Candidemia due to Candida lambica in a neutropenic oncology patient: A rare case report

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A 56-year-old cancer patient developed a serious bloodstream infection caused by a rare yeast called Candida lambica despite taking antifungal medications. Doctors identified the infection using genetic sequencing and found that the organism was sensitive to a different antifungal drug called voriconazole. After switching medications and removing the patient’s central line, the infection cleared up. This case demonstrates the importance of accurately identifying fungal infections and testing which medications work best against them.

Distribution of fungal agents in the respiratory system of patients with underlying lung diseases; molecular identification and antifungal susceptibility profiles

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This research examined fungal infections in hospitalized patients with lung diseases in Iran, identifying which fungi were most common and which antifungal medications worked best against them. Researchers found that Candida albicans and Aspergillus flavus were the most prevalent fungi, particularly in COPD patients. Notably, some Candida isolates showed resistance to certain antifungal drugs, particularly voriconazole. The study emphasizes the importance of proper fungal identification and susceptibility testing for effective treatment.

Infection caused by a cryptic fungal species, Blastomyces gilchristii, in a tiger

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A tiger at a veterinary hospital developed a serious fungal infection that affected its brain and lungs. Using advanced DNA sequencing technology, researchers identified the infection was caused by a previously unrecognized fungal species called Blastomyces gilchristii. This discovery was important because it showed that this dangerous fungus exists in areas where scientists previously thought it wasn’t found, and it highlights the importance of using modern genetic testing to identify unusual infections.

Trichosporon Urinary Tract Infections: A Hidden Menace Revealed

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Trichosporon is a fungus that causes urinary tract infections primarily in hospitalized patients and those with weakened immune systems. This review found that Trichosporon asahii is the most common species responsible for these infections, especially in patients with prolonged hospital stays or using immunosuppressive medications. The drug voriconazole works best against this fungus, while some common antifungal medications like amphotericin B are less effective. Accurate identification using modern laboratory techniques is crucial for proper treatment.

Consecutive non-Aspergillus Fungal Invasive Infections in Chronic Granulomatous Disease: Data from the French National Reference Center for Primary ImmunoDeficiencies and literature review

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This study examines rare but serious fungal infections in patients with chronic granulomatous disease, a genetic immune disorder. Researchers analyzed 122 cases of non-Aspergillus fungal infections from French hospitals and published literature, finding that these infections often occur despite preventive antifungal medications and are challenging to diagnose. The infections were found in the lungs most commonly but could spread to bones, brain, and other organs, with treatments including antifungal drugs, surgery, and in some cases bone marrow transplants.

Candidemia due to Candida lambica in a neutropenic oncology patient: A rare case report

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A 56-year-old cancer patient developed a rare blood infection caused by an unusual yeast called Candida lambica while receiving chemotherapy. Despite taking antifungal medication for prevention, the patient developed a serious fever and low white blood cell count. Doctors identified the infection through genetic testing and treated it with a different antifungal drug called voriconazole, which successfully cleared the infection.

Evaluation of Antifungal Activity Against Candida albicans Isolates From HIV-Positive Patients with Oral Candidiasis in a Major Referral Hospital, West Java, Indonesia

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This study examined fungal infections in HIV-positive patients’ mouths at an Indonesian hospital. Researchers identified which Candida species caused the infections and tested how well common antifungal medications worked against them. They found that while a specific antifungal drug (fluconazole) was effective in most cases, some infections showed resistance, suggesting the need for careful monitoring and personalized treatment approaches.

Geotrichosis Due to Magnusiomyces capitatus: A Severe Emerging Invasive Fungal Disease

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A 71-year-old cancer patient receiving chemotherapy developed a severe blood infection caused by a rare fungus called Magnusiomyces capitatus. This emerging fungal infection caused septic shock and multiple organ failure despite treatment with antifungal medications. The case highlights how these rare fungi can be deadly in patients with weakened immune systems and emphasizes the importance of quick, accurate identification using advanced laboratory techniques to guide treatment decisions.

therapeutic action: Itraconazole