therapeutic action: isavuconazole

The tell-tale hearts: Donor-derived invasive fungal infections among orthotopic heart transplant recipients

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This case report describes two rare instances where fungal infections were transmitted from organ donors to heart transplant recipients. One involved a Candida infection and the other involved Aspergillus fungus, both causing serious bloodstream and heart infections. The patients required extensive antifungal medications and multiple surgeries to survive their infections, though they experienced significant complications. These cases highlight the importance of careful screening of organ donors for undetected infections.

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When Emerging Fungal Infections Mimic Tuberculosis: First Reported Case of Invasive Emergomyces europaeus Infection in a Man With Immunocompromise Living in France

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A 65-year-old man living in France who received a kidney transplant developed a serious fungal infection caused by Emergomyces europaeus, a rare fungus that initially appeared to be tuberculosis. Doctors used advanced genetic testing to identify the unusual fungus in samples from his lungs and bone marrow. The patient was treated with a combination of antifungal medications, which successfully cleared the infection. This is the first time this particular fungal infection has been documented in France and highlights how emerging infections can mimic more common diseases.

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