therapeutic action: inhibition of fungal growth

Application of a Pickering Emulsion Stabilized by Zein and Cellulose Nanocrystalline Composite Particles to Preserve Kiwifruit

Researchers developed a new type of protective coating for kiwifruit that prevents fungal decay and extends shelf life. This coating is made from natural materials (corn protein and cellulose nanoparticles) combined with carvacrol, a natural antimicrobial compound. The coating is stable, effective, and safe for human consumption, offering a promising alternative to traditional chemical fungicides for preserving fresh fruits.

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Natamycin-Loaded Ethyl Cellulose/PVP Films Developed by Microfluidic Spinning for Active Packaging

Researchers developed special thin films that can help preserve fruits and vegetables by preventing mold growth. These films are made by combining two biodegradable polymers with an antimicrobial substance called natamycin using a new spinning technique. The films successfully inhibited gray mold, which causes major spoilage in strawberries, tomatoes, and other crops. This technology offers a promising way to extend shelf life and reduce food waste.

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The biocontrol potential of endophyte Bacillus velezensis to reduce post-harvest tomato infection caused by Rhizopus microsporus

Researchers tested a naturally occurring bacteria called Bacillus velezensis as a safe alternative to chemical fungicides for protecting tomatoes from rot-causing mold. The bacteria produces special compounds that can kill or slow down the growth of Rhizopus microsporus, a fungus that commonly spoils tomatoes after harvest. While the results show promise, the effectiveness varied depending on which specific strain of bacteria and mold was used, suggesting more research is needed to fine-tune the approach.

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Essential Oils as an Antifungal Alternative for the Control of Various Species of Fungi Isolated from Musa paradisiaca: Part I

Researchers tested six common cooking and medicinal herbs in oil form to see if they could kill fungi that damage bananas after harvest. Cinnamon oil was the most effective, successfully stopping all five types of harmful fungi at relatively low concentrations. The findings suggest these natural oils could replace harsh chemical fungicides used to preserve bananas during storage and transport, making banana production more environmentally friendly.

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Screening microbial inhibitors of Pseudogymnoascus destructans in Northern China

Scientists in Northern China have found bacteria living on bat skin and in cave soil that can kill the fungus responsible for white-nose syndrome, a disease devastating bat populations worldwide. These bacteria produce various antifungal compounds including volatile organic compounds that diffuse through the air and damage the fungus’s structure. By analyzing the genetic makeup of these bacteria, researchers identified specific genes responsible for producing these antifungal compounds, offering hope for developing biological control treatments that could protect bats and reduce fungal loads in cave environments.

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Essential Oils as an Antifungal Alternative to Control Several Species of Fungi Isolated from Musa paradisiaca: Part II

This research tested six common culinary essential oils to see if they could prevent fungi from growing on bananas after harvest. Scientists identified four types of harmful fungi that cause banana rot and tested how well oregano, rosemary, clove, thyme, cinnamon, and basil oils could stop them. The results showed that cinnamon, clove, and oregano oils were most effective at stopping fungal growth, offering a natural alternative to chemical fungicides that consumers want to avoid.

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Antifungal Activity of Sesamol on Pestalotiopsis neglecta: Interfering with Cell Membrane and Energy Metabolism

Researchers found that sesamol, a natural compound found in sesame oil, effectively kills a harmful fungus that damages pine trees and other plants. The study showed that sesamol damages the fungus’s cell membranes and disrupts its energy production, ultimately killing it. These findings suggest sesamol could be developed as a natural alternative to chemical fungicides for protecting crops and forests from disease.

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In Vitro Activity of Nitroxoline (5-Nitro-8-Hydroxyquinoline) Against Aspergillus Species

Researchers tested an old antibiotic called nitroxoline against dangerous fungal infections caused by Aspergillus species. The drug works by removing important minerals like zinc that these fungi need to survive. Testing showed nitroxoline was very effective against these fungi, even against strains that had developed resistance to modern antifungal drugs. This suggests nitroxoline could potentially be repurposed as a new treatment option for serious fungal infections.

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Biocontrol of citrus fungal pathogens by lipopeptides produced by Bacillus velezensis TZ01

Scientists discovered a beneficial bacterium called Bacillus velezensis that can protect citrus fruits from harmful fungi. This bacterium produces natural compounds called lipopeptides that kill disease-causing fungi without the need for chemical fungicides. The lipopeptides are stable and effective across different environmental conditions, making them promising for use in citrus farming as an eco-friendly alternative to traditional pesticides.

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Plants, fungi, and antifungals: A little less talk, a little more action

Plants and fungi communicate through small chemical molecules, and scientists are discovering that understanding this dialogue could lead to new antifungal medicines. Researchers found that a plant hormone called strigolactone affects a specific fungal protein involved in nutrient uptake, suggesting this could be a target for new drugs. By using baker’s yeast as a laboratory model, scientists can study how fungal cells respond to plant chemicals and identify new ways to fight dangerous fungal infections that are becoming resistant to current treatments.

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