Scientists studied how special medicinal mushroom extracts can fight advanced colon cancer in mice. They found that a blend called Agarikon Plus, especially when combined with a common chemotherapy drug, significantly improved survival rates and slowed tumor growth. By analyzing all the proteins in tumor tissues, they discovered the mushroom extracts work by disrupting the cancer cells’ ability to make proteins they need to survive and grow. This research suggests mushroom-based treatments could become important new weapons in the fight against advanced colorectal cancer.