therapeutic action: infection control

Electrospinning Enables Opportunity for Green and Effective Antibacterial Coatings of Medical Devices

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Scientists have developed a greener way to coat medical devices like wound dressings and catheters with antibacterial materials using electrospun fibers. These tiny fibers are made from natural, renewable materials and release antimicrobial agents slowly and effectively to prevent infections. Unlike traditional antibiotics that can create resistance, these coatings use multiple attack methods against bacteria, making them harder for microbes to develop resistance against.

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Continuous debridement combined with short-term posaconazole therapy for cutaneous mucormycosis caused by Rhizopus oryzae infection secondary to acute myeloid leukemia: a case report

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An 80-year-old patient with acute myeloid leukemia developed a serious fungal skin infection caused by Rhizopus oryzae on his lower leg. Doctors treated the infection by repeatedly cleaning out the infected tissue and giving him an antifungal medication called posaconazole for just one week. Despite the short treatment duration due to cost concerns, the patient’s wound gradually healed over four months through continued surgical care, showing that sometimes focused surgical treatment can be as effective as long-term medication.

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Invasive fungal otitis media with peripheral facial paralysis

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This case describes a rare fungal ear infection caused by Aspergillus fumigatus that spread to the mastoid bone and caused facial nerve paralysis. The patient had ear drainage and hearing loss for 4 years before diagnosis. Treatment required two surgical procedures to remove infected tissue combined with 6 months of antifungal medication, eventually resulting in healing and recovery of facial nerve function.

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A Case of Sphenoid Sinusitis With Epidural Abscess due to Fungal Infection and Mixed Infection With Eikenella corrodens and Aggregatibacter segnis

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A 60-year-old woman developed a severe headache caused by a fungal and bacterial infection in her sphenoid sinus (located deep in the skull). The infection spread intracranially, creating an abscess. Doctors used imaging scans to diagnose the problem, performed surgery to drain the infection and remove the fungal material, and treated the patient with antibiotics. The patient recovered completely with no recurrence after four years.

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