therapeutic action: immunomodulatory

Lipid Fraction from Agaricus brasiliensis as a Potential Therapeutic Agent for Lethal Sepsis in Mice

Researchers tested a special extract from the Agaricus brasiliensis mushroom (rich in a compound called ergosterol) to treat severe sepsis, a life-threatening blood infection, in mice. When mice were given this mushroom extract alone, 67% survived, and when combined with antibiotics, 100% survived compared to none with saline alone. The extract reduced inflammation, protected the liver, fought bacteria, and reduced harmful free radicals in the body, suggesting it could be a valuable addition to antibiotic treatment for sepsis.

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Purification, Structural Characteristics, Bioactive Properties, and Applications of Naematelia aurantialba Polysaccharides: A Comprehensive Review

Golden ear (Naematelia aurantialba) is a traditional Chinese fungus that is becoming increasingly popular for its health benefits. This comprehensive review explains how scientists extract and purify the beneficial polysaccharides from golden ear, and what makes them effective against diseases like diabetes and inflammation. The research shows these mushroom polysaccharides could be used in medicines, functional foods, and even cosmetics to improve human health.

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The First Whole Genome Sequence and Methylation Profile of Gerronema lapidescens QL01

Scientists have sequenced the complete genetic code of Lei Wan (Gerronema lapidescens), a medicinal mushroom used in traditional Chinese medicine for treating parasitic infections and digestive problems. The research revealed how this mushroom produces beneficial compounds and how its genes are regulated through a process called methylation. This information could help develop better ways to cultivate this increasingly rare mushroom sustainably rather than harvesting it from the wild, making it available for future medical research and treatment.

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