immunomodulation – Page 4

Modulating the gut microbiota is involved in the effect of low-molecular-weight Glycyrrhiza polysaccharide on immune function

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Researchers studied a natural compound from licorice called Glycyrrhiza polysaccharide (GP) to see if it could help restore immune function in mice weakened by chemotherapy. GP treatment improved intestinal health, boosted immune cells, and changed the gut bacteria composition to favor beneficial strains. The study shows that GP works partly by modifying which bacteria live in the gut, which then support the immune system. This research suggests GP could be useful as a natural supplement for strengthening immunity and treating intestinal inflammation.

Novel Synbiotic Yogurt Formulation Supplemented with Fucoidan from Phaeophyceae Algae to Promote Limosilactobacillus reuteri and Lacticaseibacillus rhamnosus GG

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Researchers developed a new yogurt containing fucoidan (a compound from brown seaweed) along with beneficial bacteria that may help reduce allergy symptoms. Testing showed this special yogurt maintained high levels of protective bacteria throughout its shelf life. The combination of the seaweed compound and beneficial bacteria could offer a natural food-based approach to help people with allergies through improved gut health.

Lentinula edodes cultured extract intake alleviates long-term immune deregulation induced by early-life gut microbiota dysbiosis

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Taking an extract from shiitake mushrooms (AHCC) during pregnancy and breastfeeding can help protect babies from the negative immune effects of antibiotics. Antibiotics given early in life damage the beneficial bacteria in the baby’s gut, leading to long-term immune problems. This study showed that shiitake extract helped restore healthy bacteria and reduced inflammation in mice exposed to antibiotics as infants, suggesting it could be used as a preventive measure for children who need antibiotics.

Research progress of edible mushroom polysaccharide-metal trace element complexes

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This research reviews how edible mushroom polysaccharides can be combined with essential metals like iron, selenium, and zinc to create health-boosting supplements. These complexes improve how our bodies absorb and use these important minerals, offering benefits like better immune function, antioxidant protection, and potential cancer-fighting properties. Scientists are studying different ways to make these complexes and testing their effectiveness for treating various health conditions.

Emerging Nonthermal Technologies for the Production of Postbiotics

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Postbiotics are dead or inactivated beneficial microorganisms and their components that support human health without needing to survive in the gut. Traditional heat-killing methods damage these beneficial compounds. This comprehensive review explores six emerging technologies that can produce postbiotics while better preserving their health-promoting properties, making them more stable and effective for food and supplement applications.

Screening and identifying natural products with SARS-CoV-2 infection inhibitory activity from medicinal fungi

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Researchers screened 167 extracts from 36 medicinal fungi to find natural compounds that could fight COVID-19. They discovered that certain fungi, particularly Inonotus obliquus and Pholiota adiposa, contain polysaccharides that effectively block the virus from infecting cells. These natural compounds showed promise as potential safe alternatives for developing new COVID-19 treatments and may have applications against other viral diseases.

Unveiling the full spectrum of maitake mushrooms: A comprehensive review of their medicinal, therapeutic, nutraceutical, and cosmetic potential

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Maitake mushrooms, long used in Asian traditional medicine, contain powerful compounds that may help fight cancer, support immune function, manage blood sugar, and protect skin health. Research shows they can inhibit bacterial and viral infections, reduce tumor growth in various cancer types, and improve overall metabolic health. These mushrooms can be incorporated into food-based supplements and skincare products. While promising results have been seen in laboratory and animal studies, more human clinical trials are needed to fully understand their benefits and safety.

In vitro antitumor effects of methanolic extracts of three Ganoderma mushrooms

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Researchers tested extracts from three types of medicinal mushrooms (Ganoderma) against cancer cells in laboratory tests. They found that one species was particularly effective against liver cancer cells, while two other species worked well against breast cancer cells. The extracts killed cancer cells while being much less harmful to normal cells, suggesting they could potentially be developed into new cancer treatments.

Valorisation of fish scales and bones: a sustainable source of bioactive proteins and collagen for nutraceuticals

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Fish scales and bones, usually thrown away as waste, contain valuable collagen and proteins that can improve skin, joints, and overall health. New extraction methods can recover these beneficial compounds efficiently while being environmentally friendly. Studies show that taking fish collagen supplements daily can improve skin appearance, reduce joint pain, and lower blood pressure, making them a sustainable and natural health solution.

Humans vs. Fungi: An Overview of Fungal Pathogens against Humans

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Fungal infections are serious health threats that kill approximately 1.5 million people annually worldwide. This comprehensive review identifies over 280 different fungal species that can infect humans, with Aspergillus being the most dangerous genus. The study provides updated information on how these infections are diagnosed through various methods including cultures, microscopy, and molecular testing, as well as treatment options ranging from traditional antifungal drugs to newer therapies like nanotechnology-based formulations.

therapeutic action: immunomodulation