therapeutic action: immune system strengthening

Selection and validation of reference genes for RT-qPCR in ophiocordyceps sinensis under different experimental conditions

mycolabadmin

Scientists studied the Chinese caterpillar mushroom (Ophiocordyceps sinensis) to find the best genes to use as reference points when measuring other gene activity. They tested sixteen potential reference genes under various stress conditions and growth stages using a technique called RT-qPCR. They found that two specific genes (18S rRNA and beta-Tubulin) were the most reliable to use as standards, which will help researchers accurately study how this medicinal mushroom responds to different conditions.

Read More »

Adaptive laboratory evolution of Blakeslea trispora under acetoacetanilide stress leads to enhanced β-carotene biosynthesis

mycolabadmin

Scientists used a technique called adaptive laboratory evolution to make a fungus called Blakeslea trispora produce much more beta-carotene, a natural compound that converts to vitamin A in the body and has health benefits. By gradually exposing the fungus to increasing levels of a chemical stressor over 16 months, they helped it evolve to produce 45% more beta-carotene. The adapted fungus showed changes in its genes, physical structure, and fat composition that helped it thrive under stress while making more of this valuable compound.

Read More »
Scroll to Top