therapeutic action: immune system enhancement

Exploring the Prebiotic Potentials of Hydrolyzed Pectins: Mechanisms of Action and Gut Microbiota Modulation

Pectins are fiber-like compounds found in fruits and vegetables that can benefit gut health by feeding beneficial bacteria. When pectins are broken down into smaller pieces (oligosaccharides), they work better as prebiotics, promoting the growth of healthy gut bacteria that produce beneficial substances called short-chain fatty acids. These compounds may help improve digestive health, strengthen immunity, and reduce inflammation.

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Proteomic study of medicinal mushroom extracts reveals antitumor mechanisms in an advanced colon cancer animal model via ribosomal biogenesis, translation, and metabolic pathways

Scientists studied how special medicinal mushroom extracts can fight advanced colon cancer in mice. They found that a blend called Agarikon Plus, especially when combined with a common chemotherapy drug, significantly improved survival rates and slowed tumor growth. By analyzing all the proteins in tumor tissues, they discovered the mushroom extracts work by disrupting the cancer cells’ ability to make proteins they need to survive and grow. This research suggests mushroom-based treatments could become important new weapons in the fight against advanced colorectal cancer.

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Changes of Active Substances in Ganoderma lucidum during Different Growth Periods and Analysis of Their Molecular Mechanism

Scientists studied how the medicinal mushroom Ganoderma lucidum changes as it grows, discovering that different growth stages contain different beneficial compounds. The budding stage was found to have the highest levels of powerful healing compounds called triterpenoids and steroids. This research helps identify the best time to harvest the mushroom to get maximum health benefits, improving both quality and standardized production for medicinal use.

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Factors governing consumers buying behavior concerning nutraceutical product

This study examines why people buy nutraceutical products like health supplements and functional foods. Key factors include knowing the health benefits, product taste and packaging, affordability and availability, and recommendations from healthcare professionals. The study found that age, education, and gender affect purchasing decisions, and online shopping has become increasingly important. Companies should focus on innovative products with simple health messages to better serve different consumer groups.

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Mitochondrial genome characterization, evolution and intron dynamics of the entomopathogenic genus Cordyceps

This research examined the genetic instruction manuals (mitochondrial DNA) of seven different Cordyceps fungal species. Scientists found that these fungi have varying amounts of genetic material, primarily due to differences in introns—sections that can be inserted or removed from genes. By comparing their genomes, researchers clarified how different Cordyceps species are related to each other evolutionarily, providing better tools for identifying and classifying these medically valuable fungi.

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Research Progress on the Mechanisms of Polysaccharides against Gastric Cancer

This review explores how natural polysaccharides from mushrooms, seaweed, plants, and traditional herbs can fight gastric cancer. These compounds work by triggering cancer cell death, stopping tumor growth, and boosting the body’s immune system. Unlike conventional chemotherapy drugs that cause serious side effects, these natural polysaccharides offer a safer alternative that can work alongside existing treatments to improve patient survival.

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Impact of Artemisia argyi and Stevia rebaudiana substrate composition on the nutritional quality, yield and mycelial growth of L. edodes addressing future food challenges

This study tested using wormwood and stevia plant waste as alternatives to traditional wood chips in shiitake mushroom farming. Results showed that adding up to 45% wormwood or 30% stevia to growing substrates increased both the amount and nutritional quality of mushrooms produced. This sustainable approach addresses mushroom farming’s resource shortage while potentially improving the nutritional value of the final product, making it beneficial for both food production and environmental protection.

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Impact of Artemisia argyi and Stevia rebaudiana substrate composition on the nutritional quality, yield and mycelial growth of L. edodes addressing future food challenges

This study shows that shiitake mushrooms can be grown on agricultural waste materials like wormwood and stevia instead of traditional sawdust. Using 45% wormwood or 30% stevia in the growing substrate improved both the mushroom yield and their nutritional content, including important compounds with health benefits. These findings suggest environmentally friendly and sustainable alternatives for mushroom farming that reduce reliance on wood resources while maintaining or improving food quality.

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The Molecular Mechanism of Polysaccharides from Polygonatum cyrtonema Hua in Improving Hyperuricemia by Regulating Key Targets of Uric Acid Metabolism in Mice

This research demonstrates that a traditional Chinese medicinal plant called Polygonatum cyrtonema contains beneficial polysaccharides that can help lower high uric acid levels in the blood, which is a major cause of gout and kidney disease. The study found that these polysaccharides work by reducing the enzyme that produces uric acid and helping the kidneys excrete more of it, while also reducing inflammation. Importantly, this natural treatment protected kidney tissue better than the standard pharmaceutical drug allopurinol, suggesting it could be a safer long-term option for managing high uric acid levels.

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Targeting SARS-CoV-2 with Chaga mushroom: An in silico study toward developing a natural antiviral compound

This study used computer modeling to investigate whether Chaga mushroom components can bind to and potentially block the coronavirus spike protein that SARS-CoV-2 uses to infect cells. The researchers found that three active compounds in Chaga—beta glycan, betulinic acid, and galactomannan—attached strongly to the virus’s binding sites in ways similar to known antiviral molecules. Beyond blocking viral entry, Chaga also has immune-boosting and anti-inflammatory properties that could help prevent the dangerous cytokine storm associated with severe COVID-19.

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