therapeutic action: Immune response enhancement

Clinically proven natural products against breast cancer, with mechanistic insights

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This comprehensive review examines ten natural products that have been proven in clinical studies to help fight breast cancer. These products—including omega-3 fatty acids from fish, compounds in broccoli sprouts, garlic, soy, curcumin from turmeric, and green tea—work by triggering cancer cells to self-destruct, stopping their growth, and preventing blood vessel formation that feeds tumors. What makes these findings especially promising is that these natural products appear to work well alongside conventional treatments while causing minimal side effects, offering patients additional options for managing this serious disease.

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Decoding small peptides: Regulators of plant growth and stress resilience

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Small peptides are tiny protein-like molecules that act as chemical messengers in plants, controlling growth, development, and how plants respond to stress. Scientists have recently developed better tools to find and study these peptides, discovering they play important roles in helping plants adapt to harsh environments like drought and disease. These findings could help create crops that are more resilient and productive, addressing challenges posed by climate change and food security.

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Evaluation of the synbiotic effects of Saccharomyces cerevisiae and mushroom extract on the growth performance, digestive enzyme activity, and immune status of zebrafish danio rerio

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Researchers tested whether combining a yeast called Saccharomyces cerevisiae with mushroom extract could improve the health and growth of zebrafish. The combination, called a synbiotic, significantly boosted fish growth by over 70%, enhanced their digestive function, and strengthened their immune system. This natural supplement approach shows promise for improving fish farming practices without requiring antibiotics.

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The Gcn5 lysine acetyltransferase mediates cell wall remodeling, antifungal drug resistance, and virulence of Candida auris

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Candida auris is a dangerous fungal infection that resists many standard antifungal drugs. Researchers discovered that a protein called Gcn5 helps this fungus survive both drugs and the body’s immune system. By targeting Gcn5 with a new compound called CPTH2, scientists showed they could make the fungus more vulnerable to standard treatments like caspofungin, suggesting a promising new approach to fighting these infections.

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Mycorrhizal symbiosis and application of vitamin B3-treated Trichoderma Harzianum HE24 additively trigger immunity responses in faba bean plants against Rhizoctonia root rot and promote the plant growth and yield

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Researchers found that combining a beneficial fungus called Trichoderma harzianum with vitamin B3 and mycorrhizal fungi can effectively protect faba bean plants from root rot caused by Rhizoctonia solani. This combined treatment boosted the plant’s natural defense systems and significantly improved plant growth and seed production. The approach offers an environmentally friendly alternative to chemical fungicides for controlling this destructive plant disease.

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