immune regulation – mycolab.ai

Application of Exercise/Training Models to Evaluate Food Functionality with Special Focus on Preventing Inflammation and Oxidative Stress and Enhancing Exercise Performance

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This review explains how different types of exercise affect your body and how specific foods can help. Moderate exercise like walking benefits from antioxidant-rich foods to reduce inflammation, while intense training requires more careful supplement selection because too much antioxidants can actually harm your training gains. The research shows that personalized approaches considering your genetics, gut bacteria, and individual responses work best for optimizing performance and health.

Screening of a Fraction with Higher Amyloid β Aggregation Inhibitory Activity from a Library Containing 210 Mushroom Extracts Using a Microliter-Scale High-Throughput Screening System with Quantum Dot Imaging

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Researchers screened 210 mushroom species from Japan to find those that could prevent harmful protein clumping in the brain associated with Alzheimer’s disease. They identified a purified fraction from the mushroom Elfvingia applanata that was more effective than a known anti-Alzheimer’s compound at stopping these protein clumps from forming. The extract also protected nerve cells from damage in laboratory tests. This finding suggests mushrooms could potentially be developed into a functional food to help prevent Alzheimer’s disease.

Use of a microbial endocrinology designed dopamine-producing probiotic to control gut neurochemical levels associated with the development of gut inflammation

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Researchers developed a special probiotic bacteria (Enterococcus faecium) that produces dopamine, a mood-boosting chemical, to reduce inflammation in chickens’ digestive systems. When combined with L-dopa (a dopamine precursor found in Mucuna beans), this probiotic successfully lowered levels of norepinephrine, a stress chemical that promotes gut inflammation. This approach could help poultry farmers improve chicken health and growth without using antibiotics, which are no longer permitted in feed.

Physicochemical properties and fermentation characteristics of a novel polysaccharide degraded from Flammulina velutipes residues polysaccharide

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Researchers developed a new method to break down a large mushroom polysaccharide from golden needle mushroom plant residues into smaller, more useful molecules. The smaller version works better as an antioxidant and helps feed beneficial gut bacteria, producing beneficial compounds that support digestive health. This discovery could lead to new functional food products and health supplements using mushroom waste that would otherwise be discarded.

Dietary melanoidins as emerging functional components: interactions with gut microbiota and implications for nutritional modulation of intestinal health

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Melanoidins are natural brown compounds formed when foods are cooked or fermented, found in items like roasted coffee, bread, and soy sauce. When eaten, these compounds pass through the stomach and small intestine unchanged, then are broken down by beneficial bacteria in the colon. This breakdown produces helpful substances that support gut health, reduce inflammation, and may help prevent digestive diseases like irritable bowel syndrome and inflammatory bowel disease.

Bioactive Potential of Tocosh Supplemented with Selenium-Enriched Saccharomyces Cerevisiae Biomass

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Researchers enhanced a traditional Peruvian fermented potato food called tocosh by adding selenium-enriched yeast. This combination reduced inflammation markers in immune cells without affecting its blood sugar impact or antioxidant properties. The resulting product shows promise as a functional food that could help people manage inflammatory conditions while improving nutritional content.

Fungal β-Glucans: Biological Properties, Immunomodulatory Effects, Diagnostic and Therapeutic Applications

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β-glucans are beneficial compounds found in fungi and some plants that help your body in multiple ways. They boost your immune system, lower cholesterol and blood sugar, protect against oxidative stress, and may help fight cancer and infections. Recent research shows they could be useful as diagnostic markers for fungal infections and as vaccine boosters, especially for diseases like COVID-19.

Comparison of Ergosterol and Vitamin D2 in Mushrooms Agaricus bisporus and Cordyceps militaris Using Ultraviolet Irradiation Directly on Dry Powder or in Ethanol Suspension

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This study shows that exposing mushroom powder suspended in ethanol to ultraviolet light effectively converts ergosterol (a natural compound in mushrooms) into vitamin D2, which is essential for bone health and immunity. The optimal treatment involves UV-C light exposure for 120 minutes at a specific distance, producing about 15 times more vitamin D2 than direct irradiation of dry mushroom powder. After removing the ethanol, these treated mushrooms could serve as a practical natural source of vitamin D for people with deficiency.

Traditional uses, chemical components and pharmacological activities of the genus Ganoderma P. Karst.: a review

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Ganoderma, a medicinal fungus used in traditional medicine for over 2000 years, contains many beneficial compounds including triterpenes and polysaccharides. Scientific research has confirmed its effectiveness in treating various conditions including cancer, diabetes, infections, and inflammation. The fungus works by boosting the immune system, reducing oxidative stress, and directly inhibiting disease-causing organisms. Modern cultivation methods have made Ganoderma products widely available as supplements and medicines worldwide.

The putatively high‐altitude adaptation of macaque monkeys: Evidence from the fecal metabolome and gut microbiome

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This study examined how macaque monkeys living on the high Tibetan Plateau adapt to harsh conditions. Researchers found that high-altitude macaques have darker feces containing more stercobilin, a pigment from red blood cell breakdown. Their gut bacteria are specially adapted to process this increased bilirubin from the extra red blood cells produced at high altitude. Interestingly, high-altitude macaques also eat medicinal mushrooms like Ganoderma lucidum, which may help them cope with the stress and low oxygen levels.

therapeutic action: immune regulation