therapeutic action: identification of epigenetic biomarkers for obesity intervention

Epigenome-wide association study of BMI and waist-to-hip ratio and their associations with dietary patterns in Korean adults

This research examined how different types of obesity (overall body weight versus belly fat) are associated with changes in DNA methylation patterns in Korean adults. The study found that certain DNA regions become less methylated in obese individuals, and that these epigenetic changes are linked to different dietary patterns. The findings suggest that specific foods may influence these epigenetic modifications differently depending on whether someone has overall obesity or more belly fat, opening new possibilities for using diet to prevent or manage obesity.

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