therapeutic action: Hypoglycemic effects

Fruiting Body Heterogeneity, Dimorphism and Haustorium-like Structure of Naematelia aurantialba (Jin Er Mushroom)

Jin Er mushroom, a popular health food in Asia, is actually made up of two different types of fungi growing together. This study discovered that Jin Er can change its form depending on temperature and nutrients, switching between yeast-like and filament-like structures. The research also found special hook-like structures that may help the two fungi interact with each other, which could help improve how Jin Er mushrooms are grown commercially.

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A putative ABC transporter gene, CcT1, is involved in beauvericin synthesis, conidiation, and oxidative stress resistance in Cordyceps chanhua

Cordyceps chanhua is a medicinal fungus used in traditional Chinese medicine that produces a compound called beauvericin, which has health benefits but can be toxic in high amounts. Researchers discovered a gene called CcT1 that controls how much beauvericin the fungus makes. By removing this gene, they could reduce beauvericin production by 64%, making the fungus safer to use as medicine while maintaining other beneficial properties.

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Recent advances in natural polysaccharides for type 2 diabetes management: sources, structural characteristics, and mechanistic insights

Natural polysaccharides from plants, mushrooms, and seaweed show promise as treatments for type 2 diabetes. These complex sugar molecules work through multiple mechanisms including improving how the body uses insulin, reducing inflammation and oxidative stress, and promoting beneficial gut bacteria. The effectiveness of these polysaccharides depends on their specific chemical structure, particularly their molecular weight and how their sugar units are linked together.

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Bioactive Metabolites from the Fruiting Body and Mycelia of Newly-Isolated Oyster Mushroom and Their Effect on Smooth Muscle Contractile Activity

Researchers isolated a new oyster mushroom strain and studied how it affects digestive system health. They compared the fruiting body and mycelium (root-like structure) and found that water extracts of the fruiting body were rich in beneficial compounds like β-glucans and antioxidants. When tested on stomach muscle tissue, these extracts caused muscle contractions in a dose-dependent manner, suggesting potential benefits for digestive function. This discovery could lead to new natural supplements supporting gut health.

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Photoregulation of the biosynthetic activity of fungus Inonotus obliquus using colloidal solutions of biogenic metal nanoparticles and low-intensity laser radiation

Scientists studied how to enhance the medicinal properties of chaga mushroom using tiny metal particles and laser light. They found that adding silver, iron, or magnesium nanoparticles to growing mushroom cultures increased biomass production. When combined with laser treatment, these nanoparticles dramatically boosted the production of beneficial compounds like polysaccharides, flavonoids, and melanin pigments that have health benefits including antioxidant and immune-boosting properties.

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Advanced Fungal Biotechnologies in Accomplishing Sustainable Development Goals (SDGs): What Do We Know and What Comes Next?

Fungi are remarkable organisms with tremendous untapped potential for solving global challenges. They can be engineered to produce life-saving medicines like antibiotics and cholesterol-lowering drugs, create nutritious food alternatives, clean up polluted environments, and help fight climate change. As we transition to more sustainable living practices, fungi represent a natural solution that has been used for centuries but is only now being fully appreciated through modern biotechnology.

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In vitro fermentation characteristics and prebiotic activity of herbal polysaccharides: a review

This review explores how plant-based polysaccharides from traditional herbs can benefit our health by feeding good bacteria in our gut. When these polysaccharides are fermented by our gut microbiota, they break down into smaller compounds that produce short-chain fatty acids, which have anti-inflammatory and immune-boosting effects. The research shows that different herbs have different structures that are recognized by specific beneficial bacteria, which suggests we can develop personalized functional foods tailored to promote specific health benefits.

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Incorporating Fresh Durum Wheat Semolina Pasta Fortified with Cardoncello (Pleurotus eryngii) Mushroom Powder as a Mediterranean Diet Staple

Researchers created a new type of pasta by mixing regular wheat pasta with powdered Cardoncello mushrooms (Pleurotus eryngii). The mushroom-enriched pasta contains significantly more fiber and antioxidants than regular pasta while maintaining good taste and texture. The product can be labeled as ‘high in fiber’ and shows promise for supporting digestive health through prebiotic effects, making it a healthier option for Mediterranean diet followers.

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Quest for Anti-SARS-CoV-2 antiviral therapeutics: in-silico and in-vitro analysis of edible mushroom- Cordyceps militaris

Researchers tested an edible mushroom called Cordyceps militaris to see if it could fight SARS-CoV-2, the virus that causes COVID-19. Using computer modeling and laboratory experiments, they found that a compound in the mushroom called cordycepin strongly attached to the virus’s spike protein and reduced viral numbers by about 50% in cell cultures. The study supports traditional uses of this mushroom and suggests it could be helpful in managing COVID-19 as the disease becomes endemic.

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